Anti-Human ZAP-70 (ABT246) Mouse Monoclonal Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: V0504

Reactivity:Human

Application:IHC,WB

Modification:Unmodified/ Total

Source:Monoclonal Mouse

Storage and Stability:Stable at -20°C for at least 1 year.

Size:

Price/Quantity $95

Quantity:

Datasheet

SDS

Immunohistochemical

Anti-Human ZAP-70 (ABT246) Mouse Monoclonal Antibody

Human appendix tissue was stained with Anti-ZAP-70 (ABT246) Antibody

Delivery

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

Telephone

408-747-0185

Fax

408-747-0145

order@assaybiotech.com

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Product Details

Product Name

Anti-Human ZAP-70 (ABT246) Mouse Monoclonal Antibody

Description

ZAP-70 is a 70 kDa tyrosine protein kinase. It belongs to the Syk family. It is expressed in T cells and NK cells, but not in most normal mature B cells. It is involved in the activation of T cell receptors. The expression of ZAP-70 is related to the mutation status, disease progression and prognosis of Ig heavy chain variable region gene in patients with chronic lymphocytic leukemia, which can be used to judge the prognosis of CLL.

Catalog No

V0504

Reactivity

Human

Application

IHC,WB

Modification

Unmodified/ Total

Source

Monoclonal Mouse

Storage and Stability

Stable at -20°C for at least 1 year.

Other Name

70 kDa zeta associated protein, 70 kDa zeta-associated protein, EC 2.7.10.2, FLJ17670, FLJ17679, Selective T cell defect, SRK, STD, Syk related tyrosine kinase, Syk-related tyrosine kinase, Truncated ZAP kinase, Tyrosine protein kinase ZAP70, Tyrosine-protein kinase ZAP-70, TZK, ZAP 70, ZAP70, ZAP70_HUMAN, Zeta chain associated protein kinase 70kD, Zeta chain associated protein kinase 70 kDa, Zeta chain associated protein kinase 70 kDa isoform 1, Zeta chain associated protein kinase 70 kDa isoform 2, Zeta chain of T cell receptor associated protein kinase 70, Zeta chain TCR associated protein kinase 70kD, Zeta chain TCR associated protein kinase 70 kDa

Gene Name

ZAP70

UniProtKB

P43403

Clone ID

ABT246

Isotype

IgG1, kappa

Localization

Cytoplasmic, Nuclear

Positive Tissue Control

Tonsil/ Appendix

Specificity

The antibody can specifically recognize human ZAP-70 protein.In western blotting of Jurkat cell lysate, the antibody can label a 70 kDa band corresponding to ZAP-70.

Formulation

PBS, pH7.2, 0.03% Proclin 300, 50% glycerol