Nucleophosmin is the most abundant nuclear phosphoprotein in cells, which usually accumulates in the cytoplasm. Generally speaking, the content of tumor growing cells is higher than that of normal quiescent cells. It can be used as a nuclear marker, as well as for the observation of the efficacy of anticancer drugs and the study of cell apoptosis.
Catalog No
V0421
Reactivity
Human
Application
IHC
Modification
Unmodified/ Total
Source
Monoclonal Mouse
Storage and Stability
Stable at -20°C for at least 1 year.
Other Name
B23, MGC104254, NO38, NPM, NPM_HUMAN, NPM1, Nucleolar phosphoprotein B23, Nucleolar protein NO38, Nucleophosmin (nucleolar phosphoprotein B23 numatrin), Nucleophosmin, nucleophosmin nucleoplasmin family member 1, Nucleophosmin/nucleoplasmin family member 1, Numatrin, OTTHUMP00000161024, OTTHUMP00000161025, OTTHUMP00000223397, OTTHUMP00000223398
Gene Name
NPM1
UniProtKB
P06748
Clone ID
ABT358
Isotype
IgG2b, kappa
Localization
Nuclear, Cytoplasmic
Positive Tissue Control
Liver
Specificity
The antibody can specifically recognize human Nucleophosmin protein.
