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Primary Antibodies
Ref-1 (Acetyl-Lys6) Antibody
Ref-1 (Acetyl-Lys6) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: D12044
Reactivity:Human,Rat,Mouse
Applications:WB,IHC,IF,ELISA
Modification:Acetyl Specific
Source:Store at -20°C/1 year
Storage and Stability:

$205
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Ref-1 (Acetyl-Lys6) Antibody

Immunofluorescence analysis of Siha cell. 1,primary Antibody was diluted at 1:100(4°C overnight). 2, Goat Anti Rabbit IgG (H&L) - AFluor 594 Secondary antibody(catalog No: SA0837) was diluted at 1:500(room temperature, 50min).

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Product Details
Product Name
Ref-1 (Acetyl-Lys6) Antibody
Description
Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site.This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein. [provided by RefSeq, Jul 2008],
Catalog No
D12044
Reactivity
Human, Rat, Mouse
Source
Polyclonal, Rabbit,IgG
Modification
Acetyl Specific
Applications
WB, IHC, IF, ELISA
Dilution
WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
APEX1; APE; APE1; APEX; APX; HAP1; REF1; DNA-(apurinic or apyrimidinic site) lyase; APEX nuclease; APEN; Apurinic-apyrimidinic endonuclease 1; AP endonuclease 1; APE-1; REF-1; Redox factor-1
Molecular Weight (Da or kDa)
Gene Name
APEX1
Protein Name
DNA-(apurinic or apyrimidinic site) lyase
Human Gene ID
328
Human Swiss Prot No.
P27695
Immunogen
The antiserum was produced against synthesized Acetyl-peptide derived from human APE1 around the Acetylation site of Lys6. AA range:1-50
Specificity
Acetyl-Ref-1 (K6) Polyclonal Antibody detects endogenous levels of Ref-1 protein only when acetylated at K6.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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