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Rb (Acetyl-K873/K874) Antibody
Rb (Acetyl-K873/K874) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: D12183
Reactivity:Human:K873+K874,Mouse:K866+K867,Rat:K865+K866
Applications:WB,IHC
Modification:Acetyl Specific
Source:Store at -20°C/1 year
Storage and Stability:

$205
Product Details
Product Name
Rb (Acetyl-K873/K874) Antibody
Description
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008],
Catalog No
D12183
Reactivity
Human:K873+K874, Mouse:K866+K867, Rat:K865+K866
Source
Polyclonal, Rabbit,IgG
Modification
Acetyl Specific
Applications
WB, IHC
Dilution
WB 1:500-2000;IHC 1:50-300
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
Retinoblastoma-associated protein (p105-Rb) (pRb) (Rb) (pp110)
Molecular Weight (Da or kDa)
106kD
Gene Name
RB1
Protein Name
Rb
Human Gene ID
5925
Human Swiss Prot No.
P06400
Immunogen
Synthesized Acetyl peptide derived from human Rb. at AA range: K873/872
Specificity
This antibody detects endogenous levels of Rb at Human:K873+K874;Mouse:K866+K867;Rat:K865+K866, It doesn't reacte with total protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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