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Primary Antibodies
Smad2/3 (Acetyl-Lys19) Antibody
Smad2/3 (Acetyl-Lys19) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: D12185
Reactivity:Human,Mouse,Rat
Applications:IHC,IF,WB
Modification:Acetyl Specific
Source:Store at -20°C/1 year
Storage and Stability:

$205
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Smad2/3 (Acetyl-Lys19) Antibody

Immunohistochemical analysis of paraffin-embedded human brain tumor. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).

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Product Details
Product Name
Smad2/3 (Acetyl-Lys19) Antibody
Description
The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein. In response to TGF-beta signal, this protein is phosphorylated by the TGF-beta receptors. The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4. The association with SMAD4 is important for the translocation
Catalog No
D12185
Reactivity
Human, Mouse, Rat
Source
Polyclonal, Rabbit,IgG
Modification
Acetyl Specific
Applications
IHC, IF, WB
Dilution
IHC 1:50-200, WB 1:500-2000. IF 1:50-200
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
Molecular Weight (Da or kDa)
Gene Name
Smad2/3 (Acetyl-Lys19)
Protein Name
Smad2/3 (Acetyl-Lys19)
Human Gene ID
4088/4087
Human Swiss Prot No.
Q15796 / P84022
Immunogen
Synthesized peptide derived from human Smad2/3 (Acetyl-Lys19)
Specificity
This antibody detects endogenous acetyl levels of Smad2/3 (Acetyl-Lys19) at Human:K19, Mouse:K19, Rat:K19
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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