PLC γ1 (Phospho-Tyr771) Antibody (A0079)

PLC γ1 (Phospho-Tyr771) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: A0079

Reactivity:Human,Mouse,Rat,Monkey

Applications:WB,IHC,IF,ELISA

Modification:Phospho Specific

Source:Store at -20°C/1 year

Storage and Stability:

Size:

Price/Quantity $205

Quantity:

Datasheet

SDS

Synthesis and Degradation

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PLC γ1 (Phospho-Tyr771) Antibody

Immunohistochemical analysis of paraffin-embedded Human breast cancer. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

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Product Details

Product Name

PLC γ1 (Phospho-Tyr771) Antibody

Description

The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Catalog No

A0079

Reactivity

Human, Mouse, Rat, Monkey

Source

Polyclonal, Rabbit,IgG

Modification

Phospho Specific

Applications

WB, IHC, IF, ELISA

Dilution

WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Storage and Stability

Store at -20°C/1 year

Other Name

PLCG1; PLC1; 1-phosphatidylinositol 4; 5-bisphosphate phosphodiesterase gamma-1; PLC-148; Phosphoinositide phospholipase C-gamma-1; Phospholipase C-II; PLC-II; Phospholipase C-gamma-1; PLC-gamma-1

Molecular Weight (Da or kDa)

Gene Name

PLCG1

Protein Name

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

Human Gene ID

5335

Human Swiss Prot No.

P19174

Immunogen

The antiserum was produced against synthesized peptide derived from human PLCG1 around the phosphorylation site of Tyr771. AA range:736-785

Specificity