Order your 5 sample sized mAbs for 77$ Order your Buy 1 get 1 on select products. Code: B1G1
Sign In/Register 0

We use cookies, check our Privacy Policies.

Products
Primary Antibodies
PI 3-kinase p85/p55 (Phospho-Tyr467/199) Antibody
PI 3-kinase p85/p55 (Phospho-Tyr467/199) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: A1224
Reactivity:Human,Mouse,Rat,Monkey,Pig
Applications:WB,IHC,IF,ELISA
Modification:Phospho Specific
Source:Store at -20°C/1 year
Storage and Stability:

$205
# Datasheet #
# SDS #
Kinases and Phosphatases
Buy One Get One
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#

PI 3-kinase p85/p55 (Phospho-Tyr467/199) Antibody

Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using PI3-kinase p85-alpha/gamma (Phospho-Tyr467/199) Antibody

Delivery
Contact Us
Telephone
408-747-0185
Fax
408-747-0145
Email
order@assaybiotech.com
Promotions
Product Details
Product Name
PI 3-kinase p85/p55 (Phospho-Tyr467/199) Antibody
Description
Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD.This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011],
Catalog No
A1224
Reactivity
Human, Mouse, Rat, Monkey, Pig
Source
Polyclonal, Rabbit,IgG
Modification
Phospho Specific
Applications
WB, IHC, IF, ELISA
Dilution
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
PIK3R1; GRB1; Phosphatidylinositol 3-kinase regulatory subunit alpha; PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase subunit p85-alpha; PtdIns-3-kinase regulatory subunit p85-alpha
Molecular Weight (Da or kDa)
Gene Name
PIK3R1/PIK3R3
Protein Name
Phosphatidylinositol 3-kinase regulatory subunit alpha/gamma
Human Gene ID
5295
Human Swiss Prot No.
P27986 / Q92569
Immunogen
The antiserum was produced against synthesized peptide derived from human PI3-kinase p85-alpha/gamma around the phosphorylation site of Tyr467/199. AA range:436-485
Specificity
Phospho-PI 3-kinase p85/p55 (Y467/199) Polyclonal Antibody detects endogenous levels of PI 3-kinase p85/p55 protein only when phosphorylated at Y467/199.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Related Products

Catalog No: A1224

PI 3-kinase p85/p55 (Phospho-Tyr467/199) Antibody

Price/Quantity:
$205

Size:
50 μl

Catalog No: B1224

PI 3-kinase p85α/γ Antibody

Price/Quantity:
$205

Size:
50 μl

Publications (21)
Maltol ameliorates intervertebral disc degeneration through inhibiting PI3K/AKT/NF-κB pathway and regulating NLRP3 inflammasome-mediated pyroptosis

Author: Available in link provided

Date of Publication : Available in link provided

Network Pharmacology Analysis and Experimental Validation to Investigate the Mechanism of Total Flavonoids of Rhizoma Drynariae in Treating Rheumatoid Arthritis WB Rat /RA-FLSs

Author: Available in link provided

Date of Publication : Available in link provided

Integrating Network Pharmacology and Experimental Validation to Explore the Key Mechanism of Gubitong Recipe in the Treatment of Osteoarthritis WB Human 1 : 1000 /SW1353 cells

Author: Available in link provided

Date of Publication : Available in link provided

TSSK4 upregulation in alveolar epithelial type-II cells facilitates pulmonary fibrosis through HSP90-AKT signaling restriction and AT-II apoptosis. Cell Death & Disease Cell Death Dis. 2021 Oct;12(10):1-14 WB Mouse MLE12 cell

Author: Available in link provided

Date of Publication : Available in link provided

Rapamycin Antagonizes BCRP-Mediated Drug Resistance Through the PI3K/Akt/mTOR Signaling Pathway in mPRα-Positive Breast Cancer. Frontiers in Oncology Front Oncol. 2021 Apr;0:352 WB Human 1 : 500 MDA-MB-231/BCRP cell，MDA-MB-453/BCRP cell

Author: Available in link provided

Date of Publication : Available in link provided

5‐FU inhibits migration and invasion of CRC cells through PI3K/AKT pathway regulated by MARCH1. CELL BIOLOGY INTERNATIONAL Cell Biol Int. 2021 Feb;45(2):368-381 WB Human Colorectal cancer(CRC ) tissues sw480s,DLD-1s,NCM460s

Author: Available in link provided

Date of Publication : Available in link provided

Polygonum cuspidatum Extract Exerts Antihyperlipidemic Effects by Regulation of PI3K/AKT/FOXO3 Signaling Pathway. Oxidative Medicine and Cellular Longevity Oxid Med Cell Longev. 2021;2021:3830671 WB Human 1:1000 HepG2 cells

Author: Available in link provided

Date of Publication : Available in link provided

Lapatinib‑induced inhibition of ovarian function is counteracted by the STAT3 pathway both in vivo and in vitro. ONCOLOGY REPORTS Oncol Rep. 2020 Sep;44(3):1127-1135 IHC Mouse 1:50 Ovarian tissue Oocytes

Author: Available in link provided

Date of Publication : Available in link provided

Deficiency in the short‐chain acyl‐CoA dehydrogenase protects mice against diet‐induced obesity and insulin resistance. FASEB JOURNAL Faseb J. 2019 Dec;33(12):13722-13733 WB Mouse liver hepatocytes

Author: Available in link provided

Date of Publication : Available in link provided

The role and regulatory mechanism of autophagy in hippocampal nerve cells of piglet damaged by deoxynivalenol. TOXICOLOGY IN VITRO Toxicol In Vitro. 2020 Aug;66:104837 WB Pig 1:1000 piglet hippocampal nerve cells (PHNCs)

Author: Available in link provided

Date of Publication : Available in link provided

Wang, Wei-wei, et al. "Telmisartan reduces atrial arrhythmia susceptibility through the regulation of RAS–ERK and PI3K–Akt–eNOS pathways in spontaneously hypertensive rats." Canadian journal of physiology and pharmacology 93.8 (2015): 657-665.

Author: Available in link provided

Date of Publication : Available in link provided

Chondroprotective Effects of Gubitong Recipe via Inhibiting Excessive Mitophagy of Chondrocytes Evidence-based Complementary and Alternative Medicine Jing Luo WB Rat

Author: Available in link provided

Date of Publication : Available in link provided

The adhesion protein of Mycoplasma genitalium inhibits urethral epithelial cell apoptosis through CypA-CD147 activating PI3K/ Akt/NF-κB pathway APPLIED MICROBIOLOGY AND BIOTECHNOLOGY Yanhua Zeng WB Human

Author: Available in link provided

Date of Publication : Available in link provided

Network and Experimental Pharmacology to Decode the Action of Wendan Decoction Against Generalized Anxiety Disorder Drug Design Development and Therapy Xin Zhao WB Mouse

Author: Available in link provided

Date of Publication : Available in link provided

Effect of STK3 on proliferation and apoptosis of pancreatic cancer cells via PI3K/AKT/mTOR pathway CELLULAR SIGNALLING Zheng Jiang WB Mouse，Human PANC-1 cell-xenograft,empty vector cell-xenograft BXPC-3 cell, PANC-1cell

Author: Available in link provided

Date of Publication : Available in link provided

AMPK/mTOR/p70S6K axis prevents apoptosis of Porphyromonas gingivalis-infected gingival epithelial cells via BadSer136 phosphorylation APOPTOSIS He Hongbing WB Human human gingival epithelial cells (hGECs)

Author: Available in link provided

Date of Publication : Available in link provided

Carbon Ions Suppress Angiogenesis and Lung Metastases in Melanoma by Targeting CXCL10. RADIATION RESEARCH Chengcheng Li WB Mouse 1: 1000 melanoma tissues

Author: Available in link provided

Date of Publication : Available in link provided

Quercetin improves cerebral ischemia/reperfusion injury by promoting microglia/macrophages M2 polarization via regulating PI3K/Akt/NF-κB signaling pathway. BIOMEDICINE & PHARMACOTHERAPY Lisheng Chu WB Rat Microglia

Author: Available in link provided

Date of Publication : Available in link provided

Cucurbitacin E reduces IL-1β-induced inflammation and cartilage degeneration by inhibiting the PI3K/Akt pathway in osteoarthritic chondrocytes Journal of Translational Medicine Wang Lin WB Human 1:1000 Chondrocytes

Author: Available in link provided

Date of Publication : Available in link provided

A novel phthalein component ameliorates neuroinflammation and cognitive dysfunction by suppressing the CXCL12/CXCR4 axis in rats with vascular dementia JOURNAL OF ETHNOPHARMACOLOGY Kai-Ting Ma WB Rat,Mouse 1:500 brain tissue BV2 cell

Author: Available in link provided

Date of Publication : Available in link provided

Taurine Inhibits Lung Metastasis in Triple-Negative Breast Cancer by Modulating Macrophage Polarization Through PTEN-PI3K/Akt/mTOR Pathway JOURNAL OF IMMUNOTHERAPY Lin Yufeng IHC Mouse Lung tissue

Author: Available in link provided

Date of Publication : Available in link provided

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
    © 2024 AssayBiotech. All Rights Reserved.
    Follow Us
    Terms of Use Privacy Policy