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Primary Antibodies
Stat1 (Phospho-Tyr701) Antibody
Stat1 (Phospho-Tyr701) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: A7222
Reactivity:Human,Mouse,Rat,Monkey
Applications:IF,WB,IHC,IP,ELISA
Modification:Phospho Specific
Source:Store at -20°C/1 year
Storage and Stability:

$205
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Stat1 (Phospho-Tyr701) Antibody

Immunofluorescence analysis of mouse-spleen tissue. 1,Stat1 (phospho Tyr701) Polyclonal Antibody(red) was diluted at 1:200(4°C,overnight). 2, Cy3 labled Secondary antibody was diluted at 1:300(room temperature, 50min).3, Picture B: DAPI(blue) 10min. Picture A:Target. Picture B: DAPI. Picture C: merge of A+B

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Product Details
Product Name
Stat1 (Phospho-Tyr701) Antibody
Description
The protein encoded byThis gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008],
Catalog No
A7222
Reactivity
Human, Mouse, Rat, Monkey
Source
Polyclonal, Rabbit,IgG
Modification
Phospho Specific
Applications
IF, WB, IHC, IP, ELISA
Dilution
IF 1:50-200 WB 1:500 - 1:2000. IHC 1:100 - 1:300. Immunoprecipitation: 2-5 ug:mg lysate. ELISA: 1:10000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
STAT1; Signal transducer and activator of transcription 1-alpha/beta; Transcription factor ISGF-3 components p91/p84
Molecular Weight (Da or kDa)
Gene Name
STAT1
Protein Name
Signal transducer and activator of transcription 1-alpha/beta
Human Gene ID
6772
Human Swiss Prot No.
P42224
Immunogen
The antiserum was produced against synthesized peptide derived from human STAT1 around the phosphorylation site of Tyr701. AA range:668-717
Specificity
Phospho-Stat1 (Y701) Polyclonal Antibody detects endogenous levels of Stat1 protein only when phosphorylated at Y701.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (5)
Suppression of the hyaluronic acid pathway induces M1 macrophages polarization via STAT1 in glioblastoma. Cell Death Discovery2022 Apr;8(1):1-13. Human U937 monocytes,U251 cell,LN229 cell

Author: Available in link provided

Date of Publication : Available in link provided

Integrated Network Pharmacology and Metabolomics Analysis to Reveal the Potential Mechanism of Siwu Paste on Aplastic Anemia Induced by Chemotherapy Drugs. Drug Design Development and Therapy2022; 16: 1231–1254. Rat BMCs

Author: Available in link provided

Date of Publication : Available in link provided

Quantitative Proteomic Analysis Reveals That Arctigenin Alleviates Concanavalin A-Induced Hepatitis Through Suppressing Immune System and Regulating Autophagy. Frontiers in Immunology 2018 Aug 16 WB Mouse liver

Author: Available in link provided

Date of Publication : Available in link provided

Quantitative Proteomic Analysis Reveals That Arctigenin Alleviates Concanavalin A-Induced Hepatitis Through Suppressing Immune System and Regulating Autophagy. Frontiers in Immunology 2018 Aug 16 WB Mouse liver

Author: Available in link provided

Date of Publication : Available in link provided

Effect of TRPM8 Functional Loss on Corneal Epithelial Wound Healing in Mice INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Lixin Xie IF Mouse Corneal

Author: Available in link provided

Date of Publication : Available in link provided

Primary Antibodies

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    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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