Trk B (Phospho-Tyr706/Y707) Antibody (A8195)

Trk B (Phospho-Tyr706/Y707) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: A8195

Reactivity:Human,Mouse,Rat

Applications:IHC,IF,ELISA

Modification:Phospho Specific

Source:Store at -20°C/1 year

Storage and Stability:

Size:

Price/Quantity $205

Quantity:

Datasheet

SDS

Neurobiology

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Trk B (Phospho-Tyr706/Y707) Antibody

Immunohistochemistry analysis of paraffin-embedded human brain, using Trk B (Phospho-Tyr706+Tyr707) Antibody. The picture on the right is blocked with the phospho peptide.

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

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408-747-0185

Fax

408-747-0145

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Product Details

Product Name

Trk B (Phospho-Tyr706/Y707) Antibody

Description

This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014],

Catalog No

A8195

Reactivity

Human, Mouse, Rat

Source

Polyclonal, Rabbit,IgG

Modification

Phospho Specific

Applications

IHC, IF, ELISA

Dilution

IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Storage and Stability

Store at -20°C/1 year

Other Name

NTRK2; TRKB; BDNF/NT-3 growth factors receptor; GP145-TrkB; Trk-B; Neurotrophic tyrosine kinase receptor type 2; TrkB tyrosine kinase; Tropomyosin-related kinase B

Molecular Weight (Da or kDa)

92kD

Gene Name

NTRK2

Protein Name

BDNF/NT-3 growth factors receptor

Human Gene ID

4915

Human Swiss Prot No.

Q16620

Immunogen

The antiserum was produced against synthesized peptide derived from human Trk B around the phosphorylation site of Tyr706 and Tyr707. AA range:676-725

Specificity

Phospho-Trk B (Y706/Y707) Polyclonal Antibody detects endogenous levels of Trk B protein only when phosphorylated at Y706/Y707.

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.