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β-Arrestin 1 (Phospho-Ser412) Antibody
β-Arrestin 1 (Phospho-Ser412) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: A9672
Reactivity:Human,Mouse,Rat
Applications:WB
Modification:Phospho Specific
Source:Polyclonal Rabbit
Storage and Stability:-20°C/1 year

$205
Product Details
Product Name
β-Arrestin 1 (Phospho-Ser412) Antibody
Description
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a Cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. [provided by RefSeq, Jan 2011]
Catalog No
A9672
Reactivity
Human, Mouse, Rat
Applications
WB
Modification
Phospho Specific
Source
Polyclonal Rabbit
Dilution
WB 1:1000-2000
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
Beta-arrestin-1 (Arrestin beta-1)
Molecular Weight (Da)
Gene Name
ARRB1 ARR1
Protein Name
β-Arrestin 1 (Ser412)
Human Gene ID
408
Human Swiss Prot No.
P49407
Immunogen
Synthesized phosho peptide around human β-Arrestin 1 (Ser412)
Specificity
This antibody detects endogenous levels of Human Mouse Rat β-Arrestin 1 (phospho-Ser412)
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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