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Primary Antibodies
PLCγ2 (Phospho-Tyr759) Antibody
PLCγ2 (Phospho-Tyr759) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: A9695
Reactivity:Human,Mouse
Applications:WB,IF,ELISA,IHC
Modification:Phospho Specific
Source:Store at -20°C/1 year
Storage and Stability:

$205
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PLCγ2 (Phospho-Tyr759) Antibody

Immunohistochemical analysis of paraffin-embedded human Gastric adenocarcinoma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).

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Product Details
Product Name
PLCγ2 (Phospho-Tyr759) Antibody
Description
The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3. [provided by RefSeq, Mar 2014],
Catalog No
A9695
Reactivity
Human, Mouse
Source
Polyclonal, Rabbit,IgG
Modification
Phospho Specific
Applications
WB, IF, ELISA, IHC
Dilution
WB 1:500-2000; IF ICC 1:50-200;ELISA 1:2000-20000;IHC 1:50-200
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-2) (Phospholipase C-IV) (PLC-IV) (Phospholipase C-gamma-2) (PLC-gamma-2)
Molecular Weight (Da or kDa)
Gene Name
PLCG2
Protein Name
PLCγ2 (Tyr759)
Human Gene ID
5336
Human Swiss Prot No.
P16885
Immunogen
Synthesized phosho peptide around human PLCγ2 (Tyr759)
Specificity
This antibody detects endogenous levels of Human Mouse PLCγ2 (phospho-Tyr759)
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (2)
Tatarinan N inhibits osteoclast differentiation through attenuating NF-κB, MAPKs and Ca2+-dependent signaling. INTERNATIONAL IMMUNOPHARMACOLOGY Int Immunopharmacol. 2018 Dec;65:199 WB Mouse bone marrow mononuclear cells (BMMs)

Author: Available in link provided

Date of Publication : Available in link provided

Tatarinan T, an α‐asarone‐derived lignin, attenuates osteoclastogenesis induced by RANKL via the inhibition of NFATc1/c‐Fos expression. CELL BIOLOGY INTERNATIONAL Cell Biol Int. 2019 Dec;43(12):1471-1482 WB Mouse Bone marrow monocytes (BMMs)

Author: Available in link provided

Date of Publication : Available in link provided

Primary Antibodies

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    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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