Sign In/Register 0

We use cookies, check our Privacy Policies.

PLC γ2 Antibody

Catalog No : B0553
  • Reactivity
    Human,Mouse,Rat
  • Applications
    WB,IHC-p,IF(paraffin section),ELISA
  • Modification
    Unmodified/Total
  • Source
    Polyclonal Rabbit
  • Storage and Stability
    -20°C/1 year
  • Size
    50 μl
  • Price/Quantity
    $205
  • Quantity
Details
  • Product Name
    PLC γ2 Antibody
  • Description
    The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3. [provided by RefSeq, Mar 2014]
  • Catalog No
    B0553
  • Reactivity
    Human, Mouse, Rat
  • Applications
    WB, IHC-p, IF(paraffin section), ELISA
  • Modification
    Unmodified/Total
  • Source
    Polyclonal Rabbit
  • Dilution
    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
  • Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration
    1 mg/ml
  • Storage and Stability
    -20°C/1 year
  • Other Name
    PLCG2; 1-phosphatidylinositol 4; 5-bisphosphate phosphodiesterase gamma-2; Phosphoinositide phospholipase C-gamma-2; Phospholipase C-IV; PLC-IV; Phospholipase C-gamma-2; PLC-gamma-2
  • Molecular Weight (Da)
    147937
  • Gene Name
    PLCG2
  • Protein Name
    1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
  • Human Gene ID
    5336
  • Human Swiss Prot No.
    P16885
  • Immunogen
    The antiserum was produced against synthesized peptide derived from human PLCG2. AA range:1186-1235
  • Specificity
    PLC γ2 Polyclonal Antibody detects endogenous levels of PLC γ2 protein.
  • Formulation
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Publications