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Btk Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: B0054
Reactivity:Human,Mouse,Rat,Monkey
Applications:WB,IHC-p,IF(paraffin section),ELISA
Modification:Unmodified/Total
Source:Polyclonal,Rabbit
Storage and Stability:Store at -20°C/1 year

$205
Product Details
Product Name
Btk Antibody
Description
AKT serine/threonine kinase 1(AKT1) Homo sapiens The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2011]
Catalog No
B0054
Reactivity
Human,Mouse,Rat,Monkey
Source
Polyclonal, Rabbit
Modification
Unmodified/Total
Applications
WB,IHC-p,IF(paraffin section),ELISA
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
Storage and Stability
Store at -20°C/1 year
Other Name
BTK; AGMX1; ATK; BPK; Tyrosine-protein kinase BTK; Agammaglobulinaemia tyrosine kinase; ATK; B-cell progenitor kinase; BPK; Bruton tyrosine kinase
Molecular Weight (Da or kDa)
76150
Gene Name
BTK
Protein Name
Tyrosine-protein kinase BTK
Human Gene ID
Human Swiss Prot No.
Q06187
Immunogen
The antiserum was produced against synthesized peptide derived from human BTK. AA range:188-237
Specificity
Btk Polyclonal Antibody detects endogenous levels of Btk protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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