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> Products > Primary Antibodies > Btk Antibody

Btk Antibody

Overview Description
Datasheet SDS
   Kinases and Phosphatases   
Catalog No : B0055
  • Reactivity
    Human,Mouse,Rat
  • Applications
    WB,ELISA
  • Modification
    Unmodified/Total
  • Source
    Polyclonal Rabbit
  • Storage and Stability
    -20°C/1 year
  • Size
    50 μl
  • Price/Quantity
    $205
  • Quantity
Add to Cart
Details
  • Product Name
    Btk Antibody
  • Description
    The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013]
  • Catalog No
    B0055
  • Reactivity
    Human, Mouse, Rat
  • Applications
    WB, ELISA
  • Modification
    Unmodified/Total
  • Source
    Polyclonal Rabbit
  • Dilution
    Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
  • Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration
    1 mg/ml
  • Storage and Stability
    -20°C/1 year
  • Other Name
    BTK; AGMX1; ATK; BPK; Tyrosine-protein kinase BTK; Agammaglobulinaemia tyrosine kinase; ATK; B-cell progenitor kinase; BPK; Bruton tyrosine kinase
  • Molecular Weight (Da)
    76150
  • Gene Name
    BTK
  • Protein Name
    Tyrosine-protein kinase BTK
  • Human Gene ID
    695
  • Human Swiss Prot No.
    Q06187
  • Immunogen
    Synthesized peptide derived from Btk . at AA range: 490-570
  • Specificity
    Btk Polyclonal Antibody detects endogenous levels of Btk protein only when non-phosphorylation at Y550.
  • Formulation
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Application Data
Western Blot analysis of 293 cells using Btk Polyclonal Antibody. Secondary antibody(catalogNo.:SA0002) was diluted at 1:20000
Application Data
Yang, Chunhui, et al. "Non-classical MHC IE negatively regulates macrophage activation and Th17 cell development in NOD mice." Scientific reports 5 (2015): 12941.
Publications

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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