ARK-1 Antibody (B0459) | Assay Biotech Inc.

ARK-1 Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: B0459

Reactivity:Human,Mouse,Rat

Applications:WB,IHC-p,IF(paraffin section),ELISA

Modification:Unmodified/Total

Source:Polyclonal,Rabbit

Storage and Stability:Store at -20°C/1 year

Size:

Price/Quantity $205

Quantity:

Datasheet

SDS

Kinases and Phosphatases

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ARK-1 Antibody

Western blot analysis of lysates from 293 cells, treated with serum 20% 15', using Aurora Kinase Antibody. The lane on the right is blocked with the synthesized peptide.

Delivery

Freight Charges

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

Telephone

408-747-0185

Fax

408-747-0145

order@assaybiotech.com

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Product Details

Product Name

ARK-1 Antibody

Description

mitogen-activated protein kinase kinase 3(MAP2K3) Homo sapiens The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for this gene. [provided by RefSeq, Jul 2008],

Catalog No

B0459

Reactivity

Human,Mouse,Rat

Source

Polyclonal, Rabbit

Modification

Unmodified/Total

Applications

WB,IHC-p,IF(paraffin section),ELISA

Dilution

Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

Storage and Stability

Store at -20°C/1 year

Other Name

AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6; Aurora kinase A; Aurora 2; Aurora/IPL1-related kinase 1; ARK-1; Aurora-related kinase 1; hARK1; Breast tumor-amplified kinase; Serine/threonine-protein kinase 15; Serine/threonin

Molecular Weight (Da or kDa)

45809

Gene Name

AURKA

Protein Name

Aurora kinase A

Human Gene ID

Human Swiss Prot No.

O14965

Immunogen

The antiserum was produced against synthesized peptide derived from human Aurora Kinase. AA range:256-305

Specificity