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JAK2 Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: B0499
Reactivity:Human,Mouse,Rat
Applications:WB,IHC-p,IF/ICC,ELISA
Modification:Unmodified/Total
Source:Polyclonal,Rabbit
Storage and Stability:Store at -20°C/1 year

$205
Product Details
Product Name
JAK2 Antibody
Description
mitogen-activated protein kinase 14(MAPK14) Homo sapiens The protein encoded byThis gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding d
Catalog No
B0499
Reactivity
Human,Mouse,Rat
Source
Polyclonal, Rabbit
Modification
Unmodified/Total
Applications
WB,IHC-p,IF/ICC,ELISA
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
Storage and Stability
Store at -20°C/1 year
Other Name
JAK2; Tyrosine-protein kinase JAK2; Janus kinase 2; JAK-2
Molecular Weight (Da or kDa)
130674
Gene Name
JAK2
Protein Name
Tyrosine-protein kinase JAK2
Human Gene ID
Human Swiss Prot No.
O60674
Immunogen
The antiserum was produced against synthesized peptide derived from human JAK2. AA range:541-590
Specificity
JAK2 Polyclonal Antibody detects endogenous levels of JAK2 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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