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Raf-1 Antibody
Raf-1 Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: B0565
Reactivity:Human,Mouse,Rat
Applications:WB,ELISA
Modification:Unmodified/Total
Source:Polyclonal,Rabbit
Storage and Stability:Store at -20°C/1 year

$205
Product Details
Product Name
Raf-1 Antibody
Description
ABL proto-oncogene 1, non-receptor tyrosine kinase(ABL1) Homo sapiens This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA-binding activity that is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function. This gene has been found fused to a variety of translocation partner genes in various leukemias, most notably the t(9;22) translocation that results in a fusion with the 5' end of the breakpoint cluster region gene (BCR; MIM:151410). Alternative splicing of this gene results in two transcript variants, which contain alternative first exons that are spliced to the remaining common exons. [pr
Catalog No
B0565
Reactivity
Human,Mouse,Rat
Source
Polyclonal, Rabbit
Modification
Unmodified/Total
Applications
WB,ELISA
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
Storage and Stability
Store at -20°C/1 year
Other Name
RAF1; RAF; RAF proto-oncogene serine/threonine-protein kinase; Proto-oncogene c-RAF; cRaf; Raf-1
Molecular Weight (Da or kDa)
73052
Gene Name
RAF1
Protein Name
RAF proto-oncogene serine/threonine-protein kinase
Human Gene ID
Human Swiss Prot No.
P04049
Immunogen
The antiserum was produced against synthesized peptide derived from human C-RAF. AA range:311-360
Specificity
Raf-1 Polyclonal Antibody detects endogenous levels of Raf-1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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