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Primary Antibodies
mTOR Antibody
mTOR Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: B0688
Reactivity:Human,Mouse,Rat
Applications:WB,IHC-p,IF(paraffin section),ELISA
Modification:Unmodified/Total
Source:Polyclonal Rabbit
Storage and Stability:-20°C/1 year

$205
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mTOR Antibody

Western blot analysis of lysates from A549 cells, using mTOR Antibody. The lane on the right is blocked with the synthesized peptide.

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408-747-0185
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408-747-0145
Email
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Product Details
Product Name
mTOR Antibody
Description
The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq, Sep 2008]
Catalog No
B0688
Reactivity
Human, Mouse, Rat
Applications
WB, IHC-p, IF(paraffin section), ELISA
Modification
Unmodified/Total
Source
Polyclonal Rabbit
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1; Serine/threonine-protein kinase mTOR; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; Mammalian target of rapamycin; mTOR; Mechanistic tar
Molecular Weight (Da)
288892
Gene Name
MTOR
Protein Name
Serine/threonine-protein kinase mTOR
Human Gene ID
2475
Human Swiss Prot No.
P42345
Immunogen
The antiserum was produced against synthesized peptide derived from human mTOR. AA range:2447-2496
Specificity
mTOR Polyclonal Antibody detects endogenous levels of mTOR protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (19)
Synthesis and anticancer evaluations of novel 1H-imidazole [4,5-f][1,10] phenanthroline derivative for the treatment of colorectal cancer

Author: Shujian Hu, Wantong Ma, Junyi Wang, Yunhao Ma, Zhongkun Zhou, Rentao Zhang, Kangjia Du, Hao Zhang, Mengze Sun, Xinrong Jiang, Hongyuan Tu, Xiaoliang Tang, Xiaojun Yao, Peng Chen

Date of Publication : 2022-06-23

Dihydroartemisinin Triggers Ferroptosis in Multidrug-Resistant Leukemia Cells

Author: Xueyan Zhang, Ziying Ai, Zhewen Zhang, Rui Dong, Lina Wang, Suya Jin, Hulai Wei

Date of Publication : 2022-06-10

MRCKα is a novel regulator of prolactin-induced lactogenesis in bovine mammary epithelial cells

Author: Fang Wang, Jürgen van Baal, Lu Ma, Xuejun Gao, Jan Dijkstra, Dengpan Bu

Date of Publication : 2022-06-09

Design, synthesis, and cytotoxic activities of isaindigotone derivatives as potential anti-gastric cancer agents

Author: Kangjia Du, Wantong Ma, Chengjie Yang, Zhongkun Zhou, Shujian Hu, Yanan Tian, Hao Zhang, Yunhao Ma, Xinrong Jiang, Hongmei Zhu, Huanxiang Liu, Peng Chen, Yingqian Liu

Date of Publication : 2022-04-21

Ganoderic acid improves 5-fluorouracil-induced cognitive dysfunction in mice

Author: Abudumijiti Abulizi, Jianhua Ran, Yuwei Ye, Yongpan An, Yukun Zhang, Zhizhen Huang, Simei Lin, Hong Zhou, Dongmei Lin, Lianfu Wang, Zhibin Lin, Min Li, Baoxue Yang

Date of Publication : 2021-11-03

3-Epipachysamine B suppresses proliferation and induces apoptosis of breast cancer cell via PI3K/AKT/mTOR signaling pathway

Author: Lei Zhang, Yi Zheng, Lizhong Zeng, Fuxin Zhang, Delu Che, Zhen Cao, Chen Huang, Liang Xian, Xinxin Zhang, Hui Zhang, Zengjun Guo

Date of Publication : 2021-09-28

Outer membrane protein a in Acinetobacter baumannii induces autophagy through mTOR signalling pathways in the lung of SD rats

Author: Dan Zhao, Yumei Li, Chunhong Peng, Jieru Lin, Fuxun Yu, Yichen Zhao, Xiangyan Zhang, Degang Zhao

Date of Publication : 2020-12-31

Copper induces energy metabolic dysfunction and AMPK-mTOR pathway-mediated autophagy in kidney of broiler chickens

Author: Jianzhao Liao, Fan Yang, Wenlan Yu, Na Qiao, Hui Zhang, Qingyue Han, Lianmei Hu, Ying Li, Jianying Guo, Jiaqiang Pan, Zhaoxin Tang

Date of Publication : 2020-09-30

CD38 is involved in cell energy metabolism via activating the PI3K/AKT/mTOR signaling pathway in cervical cancer cells

Author: Shan Liao, Lin Liang, Chunxue Yue, Junyu He, Zhengxi He, Xi Jin, Gengqiu Luo, Yanhong Zhou

Date of Publication : 2020-07-01

Relationship between PI3K/mTOR/RhoA pathway-regulated cytoskeletal rearrangements and phagocytic capacity of macrophages

Author: Bao H.R., Chen J.L., Li F., Zeng X.L., Liu X.J.

Date of Publication : 2020-06-03

Manganese Chloride Exposure Causes Disorder of Energy Metabolism and Induces Oxidative Stress and Autophagy in Chicken Liver

Author: Jiang, Jiancheng, Wang, Fengfeng, Wang, Lina, Xiao, Jiawei, Guo, Donghua

Date of Publication : 2020-01-08

RAPTOR promotes colorectal cancer proliferation by inducing mTORC1 and upregulating ribosome assembly factor URB1

Author: Tao Wang, Wei-Sheng Zhang, Zheng-Xia Wang, Zhi-Wei Wu, Bin-Bin Du, Lai-Yuan Li, Yi-Feng Chen, Xiong-Fei Yang, Xiang-Yong Hao, Tian-Kang Guo

Date of Publication : 2019-12-30

Soybean isoflavones prevent atrazine-induced neurodegenerative damage by inducing autophagy

Author: Peng Li, Xueting Li, Liyan Yao, Yanping Wu, Baixiang Li

Date of Publication : 2019-12-21

Ammonia inhalation-mediated mir-202-5p leads to cardiac autophagy through PTEN/AKT/mTOR pathway

Author: Houjuan Xing, Muqiao Peng, Zhuo Li, Jianqing Chen, Hongfu Zhang, Xiaohua Teng

Date of Publication : 2019-07-01

Targeting glycometabolic reprogramming to restore the sensitivity of leukemia drug-resistant K562/ADM cells to adriamycin

Author: Xueyan Zhang, Jing Chen, Ziying Ai, Zhewen Zhang, Li Lin, Hulai Wei

Date of Publication : 2018-10-25

Water‑soluble nano‑pearl powder promotes MC3T3‑E1 cell differentiation by enhancing autophagy via the MEK/ERK signaling pathway

Author: Yanan Cheng, Wenbai Zhang, Hui Fan, Pu Xu

Date of Publication : 2018-07-01

Cadmium induces BNIP3-dependent autophagy in chicken spleen by modulating miR-33-AMPK axis

Author: 0

Date of Publication : 2017-12-06

Insulin Attenuates Beta-Amyloid-Associated Insulin/Akt/EAAT Signaling Perturbations in Human Astrocytes

Author: Han, Xiaojuan, Yang, Liling, Du, Heng, Sun, Qinjian, Wang, Xiang, Cong, Lin, Liu, Xiaohui, Yin, Ling, Li, Shan, Du, Yifeng

Date of Publication : 2015-09-10

Ferritinophagy is involved in Bisphenol A-induced ferroptosis of renal tubular epithelial cells through the activation of the AMPK-mTOR-ULK1 pathway

Author: Lijuan Bao, Caijun Zhao, Lianjun Feng, Yihong Zhao, Shiyu Duan, Min Qiu, Keyi Wu, Naisheng Zhang, Xiaoyu Hu, Yunhe Fu

Date of Publication : 44632

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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