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> Products > Primary Antibodies > EpoR Antibody

EpoR Antibody

Overview Description
Datasheet SDS
   Membrane Receptors   
Catalog No : B0917
  • Reactivity
    Human,Mouse,Rat,Monkey
  • Applications
    WB,IF/ICC,ELISA
  • Modification
    Unmodified/Total
  • Source
    Polyclonal Rabbit
  • Storage and Stability
    -20°C/1 year
  • Size
    50 μl
  • Price/Quantity
    $205
  • Quantity
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Details
  • Product Name
    EpoR Antibody
  • Description
    This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
  • Catalog No
    B0917
  • Reactivity
    Human, Mouse, Rat, Monkey
  • Applications
    WB, IF/ICC, ELISA
  • Modification
    Unmodified/Total
  • Source
    Polyclonal Rabbit
  • Dilution
    Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
  • Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration
    1 mg/ml
  • Storage and Stability
    -20°C/1 year
  • Other Name
    EPOR; Erythropoietin receptor; EPO-R
  • Molecular Weight (Da)
    55065
  • Gene Name
    EPOR
  • Protein Name
    Erythropoietin receptor
  • Human Gene ID
    2057
  • Human Swiss Prot No.
    P19235
  • Immunogen
    The antiserum was produced against synthesized peptide derived from human Epo-R. AA range:341-390
  • Specificity
    EpoR Polyclonal Antibody detects endogenous levels of EpoR protein.
  • Formulation
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Application Data
Western blot analysis of lysates from COS7 cells, treated with EPO 20U/ml 15', using Epo-R Antibody. The lane on the right is blocked with the synthesized peptide.
Application Data
Immunofluorescence analysis of HeLa cells, using Epo-R Antibody. The picture on the right is blocked with the synthesized peptide.
Application Data
Western Blot analysis of HepG2 cells using EpoR Polyclonal Antibody

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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