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Primary Antibodies
Atm Antibody
Atm Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: B7018
Reactivity:Human,Mouse
Applications:WB,IHC,IF,ELISA
Modification:Unmodified/Total
Source:Polyclonal,Rabbit,IgG
Storage and Stability:Store at -20°C/1 year

$205
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Kinases and Phosphatases
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Atm Antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using ATM Antibody. The picture on the right is blocked with the synthesized peptide.

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Product Details
Product Name
Atm Antibody
Description
The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder. [provided by RefSeq, Aug 2010],
Catalog No
B7018
Reactivity
Human, Mouse
Source
Polyclonal, Rabbit,IgG
Modification
Unmodified/Total
Applications
WB, IHC, IF, ELISA
Dilution
WB 1:500-2000 IHC 1:100 - 1:300. ELISA: 1:40000. IF 1:50-200
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
ATM; Serine-protein kinase ATM; Ataxia telangiectasia mutated; A-T mutated
Molecular Weight (Da or kDa)
Gene Name
ATM
Protein Name
Serine-protein kinase ATM
Human Gene ID
472
Human Swiss Prot No.
Q13315
Immunogen
The antiserum was produced against synthesized peptide derived from human ATM. AA range:1950-1999
Specificity
Atm Polyclonal Antibody detects endogenous levels of Atm protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (1)
Anti-inflammatory and anti-apoptotic effects of Shaoyao decoction on X-ray radiation-induced enteritis of C57BL/6 mice J Ethnopharmacol. 2022 Mar;:115158. WB Mouse 1 : 2000 colons

Author: Available in link provided

Date of Publication : Available in link provided

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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