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Primary Antibodies
eIF2α Antibody
eIF2α Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: B7066
Reactivity:Human,Mouse,Rat,Monkey
Applications:IF/ICC,WB,IHC-p,ELISA
Modification:Unmodified/Total
Source:Polyclonal Rabbit
Storage and Stability:-20°C/1 year

$205
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eIF2α Antibody

Western Blot analysis of 3T3 cells using eIF2α Polyclonal Antibody diluted at 1:2000

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Product Details
Product Name
eIF2α Antibody
Description
The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM, Feb 2010]
Catalog No
B7066
Reactivity
Human, Mouse, Rat, Monkey
Applications
IF/ICC, WB, IHC-p, ELISA
Modification
Unmodified/Total
Source
Polyclonal Rabbit
Dilution
IF: 1:50-200 Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
EIF2S1; EIF2A; Eukaryotic translation initiation factor 2 subunit 1; Eukaryotic translation initiation factor 2 subunit alpha; eIF-2-alpha; eIF-2A; eIF-2alpha
Molecular Weight (Da)
36112
Gene Name
EIF2S1
Protein Name
Eukaryotic translation initiation factor 2 subunit 1
Human Gene ID
1965
Human Swiss Prot No.
P05198
Immunogen
The antiserum was produced against synthesized peptide derived from human eIF2 alpha. AA range:21-70
Specificity
eIF2α Polyclonal Antibody detects endogenous levels of eIF2α protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (5)
Huaier Induces Immunogenic Cell Death Via CircCLASP1/PKR/eIF2α Signaling Pathway in Triple Negative Breast Cancer

Author: Chen Li, Xiaolong Wang, Tong Chen, Wenhao Li, Xianyong Zhou, Lishui Wang, Qifeng Yang

Date of Publication : 2022-06-16

High carbohydrate diet induced endoplasmic reticulum stress and oxidative stress, promoted inflammation and apoptosis, impaired intestinal barrier of juvenile largemouth bass (Micropterus salmoides)

Author: Liulan Zhao, Ji Liang, Fukai Chen, Xiaohong Tang, Lei Liao, Qiao Liu, Jie Luo, Zongjun Du, Zhiqiong Li, Wei Luo, Song Yang, Samad Rahimnejad

Date of Publication : 2021-10-15

Endoplasmic reticulum stress-mediated autophagy activation is involved in cadmium-induced ferroptosis of renal tubular epithelial cells

Author: Caijun Zhao, Duo Yu, Zhaoqi He, Lijuan Bao, Lianjun Feng, Luotong Chen, Zhuoyu Liu, Xiaoyu Hu, Naisheng Zhang, Tiejun Wang, Yunhe Fu

Date of Publication : 2021-09-11

Overexpression of long non‐coding RNA NORAD promotes invasion and migration in malignant melanoma via regulating the MIR‐205‐EGLN2 pathway

Author: Yong Chen, Ke Cao, Jingjing Li, Aijun Wang, Lichun Sun, Jintian Tang, Wei Xiong, Xiao Zhou, Xiang Chen, Jianda Zhou, Yan Liu

Date of Publication : 2019-03-07

Enterovirus 71 Activates GADD34 via Precursor 3CD to Promote IRES-Mediated Viral Translation | Microbiology Spectrum

Author: Hui Li, Wenqian Li, Shuangling Zhang, Manman Qiu, Zhuoran Li, Yongquan Lin, Juan Tan, Wentao Qiao

Date of Publication : 44615

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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