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Primary Antibodies
GSK3β Antibody
GSK3β Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: B7098
Reactivity:Human,Mouse,Rat,Rabbit
Applications:IF,WB,IHC,IP,ELISA
Modification:Unmodified/Total
Source:Polyclonal,Rabbit,IgG
Storage and Stability:Store at -20°C/1 year

$205
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Kinases and Phosphatases
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GSK3β Antibody

Immunofluorescence analysis of rat-kidney tissue. 1,GSK3β Polyclonal Antibody(red) was diluted at 1:200(4°C,overnight). 2, Cy3 labled Secondary antibody was diluted at 1:300(room temperature, 50min).3, Picture B: DAPI(blue) 10min. Picture A:Target. Picture B: DAPI. Picture C: merge of A+B

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Product Details
Product Name
GSK3β Antibody
Description
The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009],
Catalog No
B7098
Reactivity
Human, Mouse, Rat, Rabbit
Source
Polyclonal, Rabbit,IgG
Modification
Unmodified/Total
Applications
IF, WB, IHC, IP, ELISA
Dilution
IF 1:50-200 WB 1:500 - 1:2000. IHC 1:100 - 1:300. Immunoprecipitation: 2-5 ug:mg lysate. ELISA: 1:20000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
GSK3B; Glycogen synthase kinase-3 beta; GSK-3 beta; Serine/threonine-protein kinase GSK3B
Molecular Weight (Da or kDa)
Gene Name
GSK3B
Protein Name
Glycogen synthase kinase-3 beta
Human Gene ID
2932
Human Swiss Prot No.
P49841
Immunogen
The antiserum was produced against synthesized peptide derived from human GSK3B. AA range:1-50
Specificity
GSK3β Polyclonal Antibody detects endogenous levels of GSK3β protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (16)
Mammalian elongation factor 4 regulates mitochondrial translation essential for spermatogenesis. NATURE STRUCTURAL & MOLECULAR BIOLOGY 2016 Apr 11 WB Human gastric cancer tissues

Author: Available in link provided

Date of Publication : Available in link provided

Effects of D-Chiro-Inositol on Glucose Metabolism in db/db Mice and the Associated Underlying Mechanisms. Frontiers in Pharmacology Front Pharmacol. 2020 Mar;11:354 IHC Mouse 1:250 liver tissues

Author: Available in link provided

Date of Publication : Available in link provided

PRMT5 promotes epithelial‐mesenchymal transition via EGFR‐β‐catenin axis in pancreatic cancer cells. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE 2019 Dec 18 WB Human PaTu8988 cell, SW1990 cell

Author: Available in link provided

Date of Publication : Available in link provided

PHLDA2 regulates EMT and autophagy in colorectal cancer via the PI3K/AKT signaling pathway. Aging-US Aging-Us. 2020 May 15; 12(9): 7985–8000 WB Mouse 1:1000 HCT-116 cell-Xenograft , SW480 cell-Xenograft HCT-116 cell,SW480 cell

Author: Available in link provided

Date of Publication : Available in link provided

Effects of Agriophyllum squarrosum extracts on glucose metabolism in KKAy mice and the associated underlying mechanisms. JOURNAL OF ETHNOPHARMACOLOGY J Ethnopharmacol. 2019 Sep;241:112009 WB Mouse 1:500 liver

Author: Available in link provided

Date of Publication : Available in link provided

Gene silencing of USP1 by lentivirus effectively inhibits proliferation and invasion of human osteosarcoma cells. INTERNATIONAL JOURNAL OF ONCOLOGY 2016 Dec 01 WB Human U2OS cell

Author: Available in link provided

Date of Publication : Available in link provided

Gastrointestinal Factor GDDR Attenuates Epithelial–Mesenchymal Transition in Gastric Cancer via Inhibiting AKT Signal. DIGESTIVE DISEASES AND SCIENCES Digest Dis Sci. 2016 Jul;61(7):1941-1949 WB Human gastric cancer tissues SGC7901 cell

Author: Available in link provided

Date of Publication : Available in link provided

Long noncoding RNA MALAT1 knockdown reverses chemoresistance to temozolomide via promoting microRNA‐101 in glioblastoma. Cancer Medicine Cancer Med-Us. 2018 Apr;7(4):1404-1415 WB Human 1:1000 U251 cell, U251/TMZ cell

Author: Available in link provided

Date of Publication : Available in link provided

Dickkopf Wnt signaling pathway inhibitor 1 regulates the differentiation of mouse embryonic stem cells in vitro and in vivo. Molecular Medicine Reports Mol Med Rep. 2016 Jan;13(1):720-730 WB Mouse ESCs

Author: Available in link provided

Date of Publication : Available in link provided

Environmental Enrichment Improves Spatial Learning and Memory in Vascular Dementia Rats with Activation of Wnt/β-Catenin Signal Pathway. MEDICAL SCIENCE MONITOR Med Sci Monitor. 2017; 23: 207–215 WB Rat 1: 1000 hippocampus

Author: Available in link provided

Date of Publication : Available in link provided

Cai, Tao, Yu Liu, and Jie Xiao. "Long noncoding RNA MALAT 1 knockdown reverses chemoresistance to temozolomide via promoting micro RNA‐101 in glioblastoma." Cancer medicine 7.4 (2018): 1404-1415.

Author: Available in link provided

Date of Publication : Available in link provided

Ou, Liping, et al. "Dickkopf Wnt signaling pathway inhibitor 1 regulates the differentiation of mouse embryonic stem cells in vitro and in vivo." Molecular medicine reports 13.1 (2016): 720-730.

Author: Available in link provided

Date of Publication : Available in link provided

Lu, Jian, et al. "Role of LKB1 in migration and invasion of Cr (VI)-transformed human bronchial epithelial Beas-2B cells." Anti-cancer drugs 29.7 (2018): 660-673.

Author: Available in link provided

Date of Publication : Available in link provided

PHLDA2 regulates EMT and autophagy in colorectal cancer via the PI3K/AKT signaling pathway. Aging-US Aging-Us. 2020 May 15; 12(9): 7985–8000 WB Mouse 1:1000 HCT-116 cell-Xenograft , SW480 cell-Xenograft HCT-116 cell,SW480 cell

Author: Available in link provided

Date of Publication : Available in link provided

P25/CDK5-mediated Tau Hyperphosphorylation in Both Ipsilateral and Contralateral Cerebra Contributes to Cognitive Deficits in Post-stroke Mice Current Medical Science Yu Jing WB Mouse 1:1000 Cortex,hippocampus

Author: Available in link provided

Date of Publication : Available in link provided

Dexmedetomidine facilitates autophagic flux to promote liver regeneration by suppressing GSK3β activity in mouse partial hepatectomy BIOMEDICINE & PHARMACOTHERAPY Xueya Yao WB Mouse 1:1000 liver tissue primary mouse hepatocytes,AML-12 cell

Author: Available in link provided

Date of Publication : Available in link provided

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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