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Primary Antibodies
IRS-1 Antibody
IRS-1 Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: B7122
Reactivity:Human,Mouse,Rat,Pig
Applications:WB,IHC,IF,ELISA
Modification:Unmodified/Total
Source:Polyclonal,Rabbit,IgG
Storage and Stability:Store at -20°C/1 year

$205
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IRS-1 Antibody

Immunofluorescence analysis of mouse-lung tissue. 1,IRS-1 Polyclonal Antibody(red) was diluted at 1:200(4°C,overnight). 2, Cy3 labled Secondary antibody was diluted at 1:300(room temperature, 50min).3, Picture B: DAPI(blue) 10min. Picture A:Target. Picture B: DAPI. Picture C: merge of A+B

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Product Details
Product Name
IRS-1 Antibody
Description
This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance. [provided by RefSeq, Nov 2009],
Catalog No
B7122
Reactivity
Human, Mouse, Rat, Pig
Source
Polyclonal, Rabbit,IgG
Modification
Unmodified/Total
Applications
WB, IHC, IF, ELISA
Dilution
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
IRS1; Insulin receptor substrate 1; IRS-1
Molecular Weight (Da or kDa)
Gene Name
IRS1
Protein Name
Insulin receptor substrate 1
Human Gene ID
3667
Human Swiss Prot No.
P35568
Immunogen
The antiserum was produced against synthesized peptide derived from human IRS-1. AA range:603-652
Specificity
IRS-1 Polyclonal Antibody detects endogenous levels of IRS-1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (4)
Long Non-coding RNA GAS5 Maintains Insulin Secretion by Regulating Multiple miRNAs in INS-1 832/13 Cells. Frontiers in Molecular Biosciences Front Mol Biosci. 2020; 7: 559267 WB Rat 1 : 1000 INS-1 832/13 cell

Author: Available in link provided

Date of Publication : Available in link provided

Preventative effects of resveratrol and estradiol on streptozotocin-induced diabetes in ovariectomized mice and the related mechanisms. PLoS One 2018 Oct 01 WB Mouse Skeletal muscle,myocardial tissues

Author: Available in link provided

Date of Publication : Available in link provided

Chronic heat stress increases insulin-like growth factor-1(IGF-1) but does not affect IGF-binding proteins in growing pigs. JOURNAL OF THERMAL BIOLOGY 2018 Aug 18 WB Pig 1:1000 Liver

Author: Available in link provided

Date of Publication : Available in link provided

Tao, Hong, et al. "MiR-126 suppresses the glucose-stimulated proliferation via IRS-2 in INS-1 β cells." PloS one 11.2 (2016): e0149954.

Author: Available in link provided

Date of Publication : Available in link provided

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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