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Primary Antibodies
JAK2 Antibody
JAK2 Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: B7126
Reactivity:Human,Mouse,Rat
Applications:IF,WB,IHC,ELISA
Modification:Unmodified/Total
Source:Polyclonal,Rabbit,IgG
Storage and Stability:Store at -20°C/1 year

$205
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JAK2 Antibody

Immunofluorescence analysis of rat-lung tissue. 1,JAK2 Polyclonal Antibody(red) was diluted at 1:200(4°C,overnight). 2, Cy3 labled Secondary antibody was diluted at 1:300(room temperature, 50min).3, Picture B: DAPI(blue) 10min. Picture A:Target. Picture B: DAPI. Picture C: merge of A+B

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Product Details
Product Name
JAK2 Antibody
Description
This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. [provided by RefSeq, Jul 2008],
Catalog No
B7126
Reactivity
Human, Mouse, Rat
Source
Polyclonal, Rabbit,IgG
Modification
Unmodified/Total
Applications
IF, WB, IHC, ELISA
Dilution
IF 1:50-200 WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
JAK2; Tyrosine-protein kinase JAK2; Janus kinase 2; JAK-2
Molecular Weight (Da or kDa)
Gene Name
JAK2
Protein Name
Tyrosine-protein kinase JAK2
Human Gene ID
3717
Human Swiss Prot No.
O60674
Immunogen
The antiserum was produced against synthesized peptide derived from human JAK2. AA range:981-1030
Specificity
JAK2 Polyclonal Antibody detects endogenous levels of JAK2 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (10)
Shenlian extract attenuates myocardial ischaemia-reperfusion injury via inhibiting M1 macrophage polarization by silencing miR-155

Author: Available in link provided

Date of Publication : Available in link provided

Shaoyao-Gancao Decoction Promoted Microglia M2 Polarization via the IL-13-Mediated JAK2/STAT6 Pathway to Alleviate Cerebral Ischemia-Reperfusion Injury WB Rat 1:400 penumbra tissue/

Author: Available in link provided

Date of Publication : Available in link provided

Network pharmacology analysis and experimental validation to explore the mechanism of Shenlian extract on myocardial ischemia J Ethnopharmacol. 2022 Apr;288:114973. WB Rat 1:1000 Heart

Author: Available in link provided

Date of Publication : Available in link provided

Glycerophospholipid metabolism is involved in rheumatoid arthritis pathogenesis by regulating the IL-6/JAK signaling pathway Biochem Bioph Res Co. 2022 Feb;:. WB Human 1:1000

Author: Available in link provided

Date of Publication : Available in link provided

Glycogen metabolism regulates macrophage-mediated acute inflammatory responses. Nature Communications Nat Commun. 2020 Apr;11(1):1-16 WB Mouse 1:1000 BMDMs

Author: Available in link provided

Date of Publication : Available in link provided

HIF‐1α facilitates osteocyte‐mediated osteoclastogenesis by activating JAK2/STAT3 pathway in vitro. JOURNAL OF CELLULAR PHYSIOLOGY 2019 Apr 29 WB Mouse 1:500 MLO-Y4 cell

Author: Available in link provided

Date of Publication : Available in link provided

Carbon Ion Therapy Inhibits Esophageal Squamous Cell Carcinoma Metastasis by Upregulating STAT3 Through the JAK2/STAT3 Signaling Pathway. Frontiers in Public Health Front Public Health. 2020 Nov;0:801 WB Human 1:1000 ECA109 cell， KYSE150 cell

Author: Available in link provided

Date of Publication : Available in link provided

miRNA-331-3p Affects the Proliferation, Metastasis, and Invasion of Osteosarcoma through SOCS1/JAK2/STAT3 Journal of Oncology Bing Wu WB Mouse

Author: Available in link provided

Date of Publication : Available in link provided

Shenlian extract improves atherosclerosis by relieving adventitial inflammation. JOURNAL OF ETHNOPHARMACOLOGY Xiaoxin Zhu WB Rat vascular adventitial fibroblasts (VAFs)

Author: Available in link provided

Date of Publication : Available in link provided

Overexpression of miR-506-3p reversed doxorubicin resistance in drug-resistant osteosarcoma cells Frontiers in Pharmacology Wang Xinru WB Human 1:1000 U-2OS/Dox cell

Author: Available in link provided

Date of Publication : Available in link provided

Primary Antibodies

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    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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