JNK1/2/3 Antibody (B7128) | Assay Biotech Inc.

JNK1/2/3 Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: B7128

Reactivity:Human,Mouse,Rat,Chicken(testedbyourcustomer）

Applications:WB,IHC-p,IF/ICC,ELISA

Modification:Unmodified/Total

Source:Polyclonal Rabbit

Storage and Stability:-20°C/1 year

Size:

Price/Quantity $205

Quantity:

Datasheet

SDS

Kinases and Phosphatases

JNK1/2/3 Antibody

Western Blot analysis of hela cells using JNK1/2/3 Polyclonal Antibody diluted at 1:1000

Delivery

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

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408-747-0185

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408-747-0145

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Product Details

Product Name

JNK1/2/3 Antibody

Description

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spl

Catalog No

B7128

Reactivity

Human, Mouse, Rat, Chicken(testedbyourcustomer）

Applications

WB, IHC-p, IF/ICC, ELISA

Modification

Unmodified/Total

Source

Polyclonal Rabbit

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Storage and Stability

-20°C/1 year

Other Name

MAPK8; JNK1; PRKM8; SAPK1; SAPK1C; Mitogen-activated protein kinase 8; MAP kinase 8; MAPK 8; JNK-46; Stress-activated protein kinase 1c; SAPK1c; Stress-activated protein kinase JNK1; c-Jun N-terminal kinase 1; MAPK9; JNK2; PRKM9; SAPK1A; Mi

Molecular Weight (Da)

48296/48139/52585

Gene Name

MAPK8/9/10

Protein Name

Mitogen-activated protein kinase 8/9/10

Human Gene ID

5599/5601/5602

Human Swiss Prot No.

P45983/P45984/P53779

Immunogen

The antiserum was produced against synthesized peptide derived from human SAPK/JNK. AA range:166-215

Specificity

JNK1/2/3 Polyclonal Antibody detects endogenous levels of JNK1/2/3 protein.

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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Publications (16)

Proliferatins suppress lipopolysaccharide-induced inflammation via inhibition of the NF-κB and MAPK signaling pathways

Author: Qi-xuan Kuang, Qing-zhou Li, Li-rong Lei, Yu-mei Wang, Li-jun Huang, Yi-Fei Dai, Wan Peng, Ming-zhi Zhang, Dong Wang, Yu-cheng Gu, Yun Deng, Da-le Guo

Date of Publication : 2022-04-13

The Antitriple Negative Breast cancer Efficacy of Spatholobus suberectus Dunn on ROS-Induced Noncanonical Inflammasome Pyroptotic Pathway

Author: Zhang Feng, Liu Qingqing, Ganesan Kumar, Kewu Zeng, Shen Jiangang, Gang Fang, Luo Xiaohe, Chen Jianping

Date of Publication : 2021-10-06

Adipose-Derived Stem Cells Protect Ischemia-Reperfusion and Partial Hepatectomy by Attenuating Endoplasmic Reticulum Stress

Author: Jiao Zhihui, Liu Xiaoning, Ma Yajun, Ge Yansong, Zhang Qianzhen, Liu Boyang, Wang Hongbin

Date of Publication : 2020-03-20

Novel paeonol derivatives: Design, synthesis and anti-inflammatory activity in vitro and in vivo

Author: Yang Sheng Hu, Xu Han, Pei Jing Yu, Ming Ming Jiao, Xin Hua Liu, Jing Bo Shi

Date of Publication : 2020-03-08

Dibromoacetic Acid Induced Hepatotoxicity in Mice through Oxidative Stress and Toll-Like Receptor 4 Signaling Pathway Activation

Author: Gong Tingting, Jiang Wenbo, Gao Zhijian, Chen Yingying, Gao Shuying

Date of Publication : 2019-11-20

The Effects of Maternal Atrazine Exposure and Swimming Training on Spatial Learning Memory and Hippocampal Morphology in Offspring Male Rats via PSD95/NR2B Signaling Pathway

Author: Wang, Dandan, Li, Bai, Wu, Yanping, Li, Baixiang

Date of Publication : 2019-06-11

Astragalus Polysaccharide Eases G1 Phase-Correlative Bystander Effects through Mediation of TGF-βR/MAPK/ROS Signal Pathway After Carbon Ion Irradiation in BMSCs

Author: Li-Ying Zhang, Wen-Xing Yong, Lei Wang, Li-Xin Zhang, Yi-Ming Zhang, Hong-Xia Gong, Jin-Peng He, Yong-Qi Liu

Date of Publication : 2019-05-23

Soybean Glycinin- and β-Conglycinin-Induced Intestinal Damage in Piglets via the p38/JNK/NF-κB Signaling Pathway

Author: Chenglu Peng, Chengming Cao, Mengchu He, Yingshuang Shu, Xuebing Tang, Yuanhong Wang, Yu Zhang, Xiaodong Xia, Yu Li, Jinjie Wu

Date of Publication : 2018-08-24

Astragalus Polysaccharide Inhibits Ionizing Radiation-Induced Bystander Effects by Regulating MAPK/NF-κB Signaling Pathway in Bone Mesenchymal Stem Cells (BMSCs)

Author: Liying Zhang, Yali Luo, Zhiwei Lu, Jinpeng He, Lei Wang, Lixin Zhang, Yiming Zhang, Yongqi Liu

Date of Publication : 2018-07-06

17β-Estradiol on the Expression of G-Protein Coupled Estrogen Receptor (GPER/GPR30) Mitophagy, and the PI3K/Akt Signaling Pathway in ATDC5 Chondrocytes In Vitro

Author: Dong-xiao Fan, Xu-hao Yang, Yi-nan Li, Lei Guo

Date of Publication : 2018-04-02

Cadmium induces BNIP3-dependent autophagy in chicken spleen by modulating miR-33-AMPK axis

Author: 0

Date of Publication : 2017-12-06

Inhibitory effects of oxymatrine on TGF‑β1‑induced proliferation and abnormal differentiation in rat cardiac fibroblasts via the p38MAPK and ERK1/2 signaling pathways

Author: Yini Xu, Hai Xiao, Hong Luo, Yan Chen, Yanyan Zhang, Ling Tao, Yan Jiang, Yuqi Chen, Xiangchun Shen

Date of Publication : 2017-10-01

Targeting androgen receptor with ASC-J9 attenuates cardiac injury and dysfunction in experimental autoimmune myocarditis by reducing M1-like macrophage

Author: Wenhan Ma, Ya Wang, Shuai Lu, LianHua Yan, Fen Hu, ZhaoHui Wang

Date of Publication : 2017-02-27

Administration of SB203580, a p38 MAPK Inhibitor, Reduced the Expression of MMP9, and Relieved Neurologic Severity in the Experimental Autoimmune Neuritis (EAN) in Rats

Author: Yanyan Sun, Hongping Chen, Shuainan Ma, Lixin Liang, Yi Zheng, Xiao Guo, Mingfei Wang, Wei Wang, Guozhong Li, Di Zhong

Date of Publication : 2015-05-22

Selected lactobacilli strains inhibit inflammation in LPS-induced RAW264.7 macrophages by suppressing the TLR4-mediated NF-κB and MAPKs activation

Author: SHI Jialu, LI Huizhen, LIANG Shengnan, EVIVIE Smith Etareri, HUO Guicheng, LI Bailiang, LIU Fei

Date of Publication : 44638

Therapeutic Potential of Synthetic Human β-Defensin 1 Short Motif Pep-B on Lipopolysaccharide-Stimulated Human Dental Pulp Stem Cells

Author: Shi Jue, Hu Zihe, Zhou Yanyan, Zuo Minghao, Wu Haiyan, Jin Wenjing, Xie Zhijian

Date of Publication : 44585

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Catalog No: B7128

Reactivity:Human,Mouse,Rat,Chicken(testedbyourcustomer）

Applications:WB,IHC-p,IF/ICC,ELISA

Modification:Unmodified/Total

Source:Polyclonal Rabbit

Storage and Stability:-20°C/1 year

JNK1/2/3 Antibody

IRAK-1 (Phospho-Thr209) Antibody

COL1A2 Antibody

SYP Antibody

TNF-α Antibody

β-actin Monoclonal Antibody(5B7)

GAPDH Monoclonal Antibody(2B8)

HRP* Goat Anti Mouse IgG(H+L)

HRP* Goat Anti Rabbit IgG(H+L)

Proliferatins suppress lipopolysaccharide-induced inflammation via inhibition of the NF-κB and MAPK signaling pathways

The Antitriple Negative Breast cancer Efficacy of Spatholobus suberectus Dunn on ROS-Induced Noncanonical Inflammasome Pyroptotic Pathway

Adipose-Derived Stem Cells Protect Ischemia-Reperfusion and Partial Hepatectomy by Attenuating Endoplasmic Reticulum Stress

Novel paeonol derivatives: Design, synthesis and anti-inflammatory activity in vitro and in vivo

Dibromoacetic Acid Induced Hepatotoxicity in Mice through Oxidative Stress and Toll-Like Receptor 4 Signaling Pathway Activation

The Effects of Maternal Atrazine Exposure and Swimming Training on Spatial Learning Memory and Hippocampal Morphology in Offspring Male Rats via PSD95/NR2B Signaling Pathway

Astragalus Polysaccharide Eases G1 Phase-Correlative Bystander Effects through Mediation of TGF-βR/MAPK/ROS Signal Pathway After Carbon Ion Irradiation in BMSCs

Soybean Glycinin- and β-Conglycinin-Induced Intestinal Damage in Piglets via the p38/JNK/NF-κB Signaling Pathway

Astragalus Polysaccharide Inhibits Ionizing Radiation-Induced Bystander Effects by Regulating MAPK/NF-κB Signaling Pathway in Bone Mesenchymal Stem Cells (BMSCs)

17β-Estradiol on the Expression of G-Protein Coupled Estrogen Receptor (GPER/GPR30) Mitophagy, and the PI3K/Akt Signaling Pathway in ATDC5 Chondrocytes In Vitro

Cadmium induces BNIP3-dependent autophagy in chicken spleen by modulating miR-33-AMPK axis

Inhibitory effects of oxymatrine on TGF‑β1‑induced proliferation and abnormal differentiation in rat cardiac fibroblasts via the p38MAPK and ERK1/2 signaling pathways

Targeting androgen receptor with ASC-J9 attenuates cardiac injury and dysfunction in experimental autoimmune myocarditis by reducing M1-like macrophage

Administration of SB203580, a p38 MAPK Inhibitor, Reduced the Expression of MMP9, and Relieved Neurologic Severity in the Experimental Autoimmune Neuritis (EAN) in Rats

Selected lactobacilli strains inhibit inflammation in LPS-induced RAW264.7 macrophages by suppressing the TLR4-mediated NF-κB and MAPKs activation

Therapeutic Potential of Synthetic Human β-Defensin 1 Short Motif Pep-B on Lipopolysaccharide-Stimulated Human Dental Pulp Stem Cells

Primary Antibodies

ELISA Kits

Research Areas

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