This gene encodes a member of the casein kinase I gene family. This family is comprised of serine/threonine kinases that phosphorylate acidic proteins such as caseins. The encoded kinase plays a role in cell cycle checkpoint arrest in response to stalled replication forks by phosphorylating Claspin. A mutation in this gene may be associated with non-syndromic early-onset epilepsy (NSEOE). [provided by RefSeq, Jul 2016]
Catalog No
B8089
Reactivity
Human, Mouse, Rat
Applications
IHC-p, IF(paraffin section), ELISA
Modification
Unmodified/Total
Source
Polyclonal Rabbit
Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
CSNK1G1; Casein kinase I isoform gamma-1; CKI-gamma 1; CSNK1G2; CK1G2; Casein kinase I isoform gamma-2; CKI-gamma 2; CSNK1G3; Casein kinase I isoform gamma-3; CKI-gamma 3
Molecular Weight (Da)
48511/47457/51389
Gene Name
CSNK1G1/CSNK1G2/CSNK1G3
Protein Name
Casein kinase I isoform gamma-1/2/3
Human Gene ID
53944/1455/1456
Human Swiss Prot No.
Q9HCP0/P78368/Q9Y6M4
Immunogen
The antiserum was produced against synthesized peptide derived from human CK-1gamma1/2/3. AA range:229-278
Immunohistochemical analysis of paraffin-embedded Human brain. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
