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Primary Antibodies
Tak1 Antibody
Tak1 Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: B8132
Reactivity:Human,Mouse,Rat
Applications:IF,WB,IHC,ELISA
Modification:Unmodified/Total
Source:Polyclonal,Rabbit,IgG
Storage and Stability:Store at -20°C/1 year

$205
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Kinases and Phosphatases
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Tak1 Antibody

Immunofluorescence analysis of human-stomach tissue. 1,Tak1 Polyclonal Antibody(red) was diluted at 1:200(4°C,overnight). 2, Cy3 labled Secondary antibody was diluted at 1:300(room temperature, 50min).3, Picture B: DAPI(blue) 10min. Picture A:Target. Picture B: DAPI. Picture C: merge of A+B

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Product Details
Product Name
Tak1 Antibody
Description
The protein encoded byThis gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008],
Catalog No
B8132
Reactivity
Human, Mouse, Rat
Source
Polyclonal, Rabbit,IgG
Modification
Unmodified/Total
Applications
IF, WB, IHC, ELISA
Dilution
IF 1:50-200 WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
MAP3K7; TAK1; Mitogen-activated protein kinase kinase kinase 7; Transforming growth factor-beta-activated kinase 1; TGF-beta-activated kinase 1
Molecular Weight (Da or kDa)
Gene Name
MAP3K7
Protein Name
Mitogen-activated protein kinase kinase kinase 7
Human Gene ID
6885
Human Swiss Prot No.
O43318
Immunogen
The antiserum was produced against synthesized peptide derived from human MAP3K7. AA range:161-210
Specificity
Tak1 Polyclonal Antibody detects endogenous levels of Tak1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (6)
RNA-induced liquid phase separation of SARS-CoV-2 nucleocapsid protein facilitates NF-κB hyper-activation and inflammation. Signal Transduction and Targeted Therapy Signal Transduct Tar. 2021 Apr;6(1):1-13 IF，WB Human HEK293T cell

Author: Available in link provided

Date of Publication : Available in link provided

Exercise ameliorates insulin resistance via regulating TGFβ‐activated kinase 1 (TAK1)‐mediated insulin signaling in liver of high‐fat diet‐induced obese rats. JOURNAL OF CELLULAR PHYSIOLOGY 2018 Oct 26 WB Rat 1:1000 liver tissues

Author: Available in link provided

Date of Publication : Available in link provided

Exercise ameliorates insulin resistance via regulating TGFβ‐activated kinase 1 (TAK1)‐mediated insulin signaling in liver of high‐fat diet‐induced obese rats. JOURNAL OF CELLULAR PHYSIOLOGY 2018 Oct 26 WB Rat 1:1000 liver tissues

Author: Available in link provided

Date of Publication : Available in link provided

Exercise ameliorates insulin resistance via regulating TGFβ‐activated kinase 1 (TAK1)‐mediated insulin signaling in liver of high‐fat diet‐induced obese rats. JOURNAL OF CELLULAR PHYSIOLOGY 2018 Oct 26 WB Rat 1:1000 liver tissues

Author: Available in link provided

Date of Publication : Available in link provided

Alpha-Momorcharin Inhibits Proinflammatory Cytokine Expression by M1 Macrophages but Not Anti-Inflammatory Cytokine Expression by M2 Macrophages Journal of Inflammation Research Fubing Shen WB Human

Author: Available in link provided

Date of Publication : Available in link provided

Upregulation of TRIM16 mitigates doxorubicin-induced cardiotoxicity by modulating TAK1 and YAP/Nrf2 pathways in mice BIOCHEMICAL PHARMACOLOGY Xinyu Guo WB,IP Mouse,Rat 1:1000 heart tissue Neonatal rat cardiomyocytes (NRCMs)

Author: Available in link provided

Date of Publication : Available in link provided

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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