Sign In/Register 0

We use cookies, check our Privacy Policies.

PRAK Antibody

Catalog No : B8364
  • Reactivity
    Human,Mouse
  • Applications
    WB,ELISA
  • Modification
    Unmodified/Total
  • Source
    Polyclonal Rabbit
  • Storage and Stability
    -20°C/1 year
  • Size
    50 μl
  • Price/Quantity
    $205
  • Quantity
Details
  • Product Name
    PRAK Antibody
  • Description
    The protein encoded by this gene is a tumor suppressor and member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. The encoded protein is found in the nucleus but translocates to the Cytoplasm upon phosphorylation and activation. This kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Nov 2012]
  • Catalog No
    B8364
  • Reactivity
    Human, Mouse
  • Applications
    WB, ELISA
  • Modification
    Unmodified/Total
  • Source
    Polyclonal Rabbit
  • Dilution
    Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
  • Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration
    1 mg/ml
  • Storage and Stability
    -20°C/1 year
  • Other Name
    MAPKAPK5; PRAK; MAP kinase-activated protein kinase 5; MAPK-activated protein kinase 5; MAPKAP kinase 5; MAPKAP-K5; MAPKAPK-5; MK-5; MK5; p38-regulated/activated protein kinase; PRAK
  • Molecular Weight (Da)
    54220
  • Gene Name
    MAPKAPK5
  • Protein Name
    MAP kinase-activated protein kinase 5
  • Human Gene ID
    8550
  • Human Swiss Prot No.
    Q8IW41
  • Immunogen
    The antiserum was produced against synthesized peptide derived from human MAPKAPK5. AA range:148-197
  • Specificity
    PRAK Polyclonal Antibody detects endogenous levels of PRAK protein.
  • Formulation
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.