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Primary Antibodies
SIRT1 Antibody
SIRT1 Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: B8476
Reactivity:Human,Mouse
Applications:IF,WB,IHC,ELISA
Modification:Unmodified/Total
Source:Polyclonal,Rabbit,IgG
Storage and Stability:Store at -20°C/1 year

$205
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SIRT1 Antibody

Immunofluorescence analysis of rat-lung tissue. 1,SIRT1 Polyclonal Antibody(red) was diluted at 1:200(4°C,overnight). 2, Cy3 labled Secondary antibody was diluted at 1:300(room temperature, 50min).3, Picture B: DAPI(blue) 10min. Picture A:Target. Picture B: DAPI. Picture C: merge of A+B

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Product Details
Product Name
SIRT1 Antibody
Description
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity.The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008],
Catalog No
B8476
Reactivity
Human, Mouse
Source
Polyclonal, Rabbit,IgG
Modification
Unmodified/Total
Applications
IF, WB, IHC, ELISA
Dilution
IF 1:50-200 WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
SIRT1; SIR2L1; NAD-dependent protein deacetylase sirtuin-1; hSIRT1; Regulatory protein SIR2 homolog 1; SIR2-like protein 1; hSIR2
Molecular Weight (Da or kDa)
Gene Name
SIRT1
Protein Name
NAD-dependent protein deacetylase sirtuin-1
Human Gene ID
23411
Human Swiss Prot No.
Q96EB6
Immunogen
The antiserum was produced against synthesized peptide derived from human SirT1. AA range:13-62
Specificity
SIRT1 Polyclonal Antibody detects endogenous levels of SIRT1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (5)
CD38 affects the biological behavior and energy metabolism of nasopharyngeal carcinoma cells. INTERNATIONAL JOURNAL OF ONCOLOGY Int J Oncol. 2019 Feb;54(2):585-599 WB Human 1:1000 5-8F cell

Author: Available in link provided

Date of Publication : Available in link provided

Gut-Flora-Dependent Metabolite Trimethylamine-N-Oxide Promotes Atherosclerosis-Associated Inflammation Responses by Indirect ROS Stimulation and Signaling Involving AMPK and SIRT1 Nutrients Wenjian Ma WB Human

Author: Available in link provided

Date of Publication : Available in link provided

Melatonin alleviates doxorubicin-induced cardiotoxicity via inhibiting oxidative stress, pyroptosis and apoptosis by activating Sirt1/Nrf2 pathway BIOMEDICINE & PHARMACOTHERAPY Congxin Huang WB Rat,Mouse heart H9C2 cell

Author: Available in link provided

Date of Publication : Available in link provided

m6A-Dependent Modulation via IGF2BP3/MCM5/Notch Axis Promotes Partial EMT and LUAD Metastasis. Junchao Cai WB Human A549 cell,HEK293FT cell

Author: Available in link provided

Date of Publication : Available in link provided

Alternate-day fasting ameliorated anxiety-like behavior in high-fat diet-induced obese mice JOURNAL OF NUTRITIONAL BIOCHEMISTRY Huijuan Hu WB Mouse 1:1000 hippocampal tissue

Author: Available in link provided

Date of Publication : Available in link provided

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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