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Primary Antibodies
Caveolin-1 Antibody
Caveolin-1 Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C0139
Reactivity:Human,Mouse,Rat
Applications:WB,IHC-p,IF/ICC,ELISA
Modification:Unmodified/Total
Source:Polyclonal Rabbit
Storage and Stability:-20°C/1 year

$205
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Caveolin-1 Antibody

Western Blot analysis of HuvEc cells using Caveolin-1 Polyclonal Antibody diluted at 1:1000

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Product Details
Product Name
Caveolin-1 Antibody
Description
The scaffolding protein encoded by this gene is the main component of the caveolae Plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.[provided by RefSeq, Mar 2010]
Catalog No
C0139
Reactivity
Human, Mouse, Rat
Applications
WB, IHC-p, IF/ICC, ELISA
Modification
Unmodified/Total
Source
Polyclonal Rabbit
Dilution
WB 1:500-2000, IF 1:50-300, IHC 1:50-300
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
CAV1; CAV; Caveolin-1
Molecular Weight (Da)
20472
Gene Name
CAV1
Protein Name
Caveolin-1
Human Gene ID
857
Human Swiss Prot No.
Q03135
Immunogen
The antiserum was produced against synthesized peptide derived from human Caveolin-1. AA range:129-178
Specificity
Caveolin-1 Polyclonal Antibody detects endogenous levels of Caveolin-1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (1)
Caveolin-1 affects tumor drug resistance in esophageal squamous cell carcinoma by regulating expressions of P-gp and MRP1

Author: Song Zhang, Wenbo Cao, Mingjin Yue, Naigang Zheng, Tao Hu, Shengli Yang, Ziming Dong, Shixin Lu, Saijun Mo

Date of Publication : 2016-01-14

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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