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Primary Antibodies
Connexin 43 Antibody
Connexin 43 Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C0158
Reactivity:Human,Mouse,Rat
Applications:WB,IHC,IF,ELISA
Modification:Unmodified/Total
Source:Polyclonal,Rabbit,IgG
Storage and Stability:Store at -20°C/1 year

$205
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Cell Adhesion Proteins
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Connexin 43 Antibody

Immunofluorescence analysis of mouse-heart tissue. 1,Connexin 43 Polyclonal Antibody(red) was diluted at 1:200(4°C,overnight). 2, Cy3 labled Secondary antibody was diluted at 1:300(room temperature, 50min).3, Picture B: DAPI(blue) 10min. Picture A:Target. Picture B: DAPI. Picture C: merge of A+B

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Product Details
Product Name
Connexin 43 Antibody
Description
This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia, autosomal recessive craniometaphyseal dysplasia and heart malformations. [provided by RefSeq, May 2014],
Catalog No
C0158
Reactivity
Human, Mouse, Rat
Source
Polyclonal, Rabbit,IgG
Modification
Unmodified/Total
Applications
WB, IHC, IF, ELISA
Dilution
WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000. IF 1:100-300 Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
GJA1; GJAL; Gap junction alpha-1 protein; Connexin-43; Cx43; Gap junction 43 kDa heart protein
Molecular Weight (Da or kDa)
Gene Name
GJA1
Protein Name
Gap junction alpha-1 protein
Human Gene ID
2697
Human Swiss Prot No.
P17302
Immunogen
The antiserum was produced against synthesized peptide derived from human Connexin 43. AA range:333-382
Specificity
Connexin 43 Polyclonal Antibody detects endogenous levels of Connexin 43 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (7)
Mussel‐Inspired Conductive Cryogel as Cardiac Tissue Patch to Repair Myocardial Infarction by Migration of Conductive Nanoparticles. ADVANCED FUNCTIONAL MATERIALS 2016 Apr 27 WB,IF Rat 1:100 cardiomyocytes

Author: Available in link provided

Date of Publication : Available in link provided

PDGF-mediated PI3K/AKT/β-catenin signaling regulates gap junctions in corpus cavernosum smooth muscle cells. EXPERIMENTAL CELL RESEARCH Exp Cell Res. 2018 Jan;362:252 WB Rat 1:1000 corpus cavernosum smooth muscle cells (CCSMCs)

Author: Available in link provided

Date of Publication : Available in link provided

P6 Electroacupuncture Improved QTc Interval Prolongation by Upregulation of Connexin43 in Droperidol Treated Rats. Evidence-based Complementary and Alternative Medicine Evid-Based Compl Alt. 2014;2014:926423 WB Rat 1 : 1000 ventricle

Author: Available in link provided

Date of Publication : Available in link provided

The use of antibody modified liposomes loaded with AMO-1 to deliver oligonucleotides to ischemic myocardium for arrhythmia therapy. BIOMATERIALS Biomaterials. 2014 Apr;35:3697 IHC Rat 1:100 left ventricle

Author: Available in link provided

Date of Publication : Available in link provided

The use of antibody modified liposomes loaded with AMO-1 to deliver oligonucleotides to ischemic myocardium for arrhythmia therapy. BIOMATERIALS Biomaterials. 2014 Apr;35:3697 IHC Rat 1:100 left ventricle

Author: Available in link provided

Date of Publication : Available in link provided

Muscone attenuates susceptibility to ventricular arrhythmia by inhibiting NLRP3 inflammasome activation in rats after myocardial infarction. Yanhong Tang IHC，WB Rat 1:1000，1:1000 hearts

Author: Available in link provided

Date of Publication : Available in link provided

Genotoxicity of bisphenol AF in rats: Detrimental to male reproductive system and probable stronger micronucleus induction potency than BPA. JOURNAL OF APPLIED TOXICOLOGY Jinyao Chen IHC Rat testis

Author: Available in link provided

Date of Publication : Available in link provided

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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