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Primary Antibodies
Desmin Antibody
Desmin Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C0171
Reactivity:Human,Mouse,Rat
Applications:WB,IHC,IF,ELISA
Modification:Unmodified/Total
Source:Store at -20°C/1 year
Storage and Stability:

$205
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Desmin Antibody

Immunofluorescence analysis of Hela cell. 1,Desmin Polyclonal Antibody(green) was diluted at 1:200(4° overnight). 2, Goat Anti Rabbit Alexa Fluor 488 Catalog:SA0665 was diluted at 1:1000(room temperature, 50min). 3 DAPI(blue) 10min.

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Product Details
Product Name
Desmin Antibody
Description
This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. [provided by RefSeq, Jul 2008],
Catalog No
C0171
Reactivity
Human, Mouse, Rat
Source
Polyclonal, Rabbit,IgG
Modification
Unmodified/Total
Applications
WB, IHC, IF, ELISA
Dilution
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
DES; Desmin
Molecular Weight (Da or kDa)
Gene Name
DES
Protein Name
P17661
Human Gene ID
The antiserum was produced against synthesized peptide derived from human Desmin. AA range:421-470
Human Swiss Prot No.
Desmin Polyclonal Antibody detects endogenous levels of Desmin protein.
Immunogen
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
Formulation
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Publications (8)
Exosome-delivered EGFR regulates liver microenvironment to promote gastric cancer liver metastasis. Nature Communications 2017 Apr 10 WB,IF Human,Mouse 1:1000 liver,SGC7901 cell-xenograft SGC7901 cell

Author: Available in link provided

Date of Publication : Available in link provided

MicroRNA-182 Regulates Neurite Outgrowth Involving the PTEN/AKT Pathway. Frontiers in Cellular Neuroscience 2017 Apr 10 WB,IF Mouse 1:1000 primary liver cell

Author: Available in link provided

Date of Publication : Available in link provided

The PI3K/p-Akt signaling pathway participates in calcitriol ameliorating podocyte injury in DN rats. METABOLISM-CLINICAL AND EXPERIMENTAL Metabolism. 2014 Oct;63:1324 WB Rat Renal tissues

Author: Available in link provided

Date of Publication : Available in link provided

Podocyte-specific Rac1 deficiency ameliorates podocyte damage and proteinuria in STZ-induced diabetic nephropathy in mice. Cell Death & Disease Cell Death Dis. 2018 Mar;9(3):1-15 WB Mouse podocytes

Author: Available in link provided

Date of Publication : Available in link provided

LncRNA MALAT1 is dysregulated in diabetic nephropathy and involved in high glucose‐induced podocyte injury via its interplay with β‐catenin. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE 2017 Apr 26 WB Mouse 1:1500 podocytes

Author: Available in link provided

Date of Publication : Available in link provided

PDGF-mediated PI3K/AKT/β-catenin signaling regulates gap junctions in corpus cavernosum smooth muscle cells. EXPERIMENTAL CELL RESEARCH Exp Cell Res. 2018 Jan;362:252 IF Rat 1:100 SMCs

Author: Available in link provided

Date of Publication : Available in link provided

Fyn Mediates High Glucose-Induced Actin Cytoskeleton Reorganization of Podocytes via Promoting ROCK Activation In Vitro. Journal of Diabetes Research J Diabetes Res. 2016;2016:5671803 IF Mouse podocytes

Author: Available in link provided

Date of Publication : Available in link provided

Hu, Mengsi, et al. "Lnc RNA MALAT 1 is dysregulated in diabetic nephropathy and involved in high glucose‐induced podocyte injury via its interplay with β‐catenin." Journal of cellular and molecular medicine 21.11 (2017): 2732-2747.

Author: Available in link provided

Date of Publication : Available in link provided

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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