The protein encoded by this gene belongs to the histone deacetylase family, members of which deacetylate lysine residues on the N-terminal part of the core histones. Histone deacetylation modulates chromatin structure, and plays an important role in transcriptional regulation, cell cycle progression, and developmental events. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
Catalog No
C0222
Reactivity
Human, Mouse, Rat, Monkey
Applications
WB, IHC-p, IF(paraffin section), ELISA
Modification
Acetyl Specific
Source
Polyclonal Rabbit
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
HDAC10; Histone deacetylase 10; HD10
Molecular Weight (Da)
71445
Gene Name
HDAC10
Protein Name
Histone deacetylase 10
Human Gene ID
83933
Human Swiss Prot No.
Q969S8
Immunogen
The antiserum was produced against synthesized peptide derived from human HDAC10. AA range:10-59
Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using HDAC10 Antibody. The picture on the right is blocked with the synthesized peptide.
