Description
This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of Extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down fibronectin, laminin, elastin, proteoglycan core protein, gelatins, and several types of collagen. The gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016]
Reactivity
Human, Mouse, Rat
Applications
IHC-p, IF/ICC, WB, ELISA
Modification
Unmodified/Total
Source
Polyclonal Rabbit
Dilution
WB 1:500-2000 Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
MMP10; STMY2; Stromelysin-2; SL-2; Matrix metalloproteinase-10; MMP-10; Transin-2
Molecular Weight (Da)
54151
Gene Name
MMP10
Protein Name
Stromelysin-2
Human Gene ID
4319
Human Swiss Prot No.
P09238
Immunogen
The antiserum was produced against synthesized peptide derived from human MMP-10. AA range:361-410
Specificity
MMP-10 Polyclonal Antibody detects endogenous levels of MMP-10 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
