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Primary Antibodies
MMP-2 Antibody
MMP-2 Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C0270
Reactivity:Human,Mouse,Rat,Monkey
Applications:WB,IHC-p,IF/ICC,ELISA
Modification:Unmodified/Total
Source:Polyclonal Rabbit
Storage and Stability:-20°C/1 year

$205
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MMP-2 Antibody

Western Blot analysis of HT29 cells using MMP-2 Polyclonal Antibody diluted at 1:1000

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Contact Us
Telephone
408-747-0185
Fax
408-747-0145
Email
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Product Details
Product Name
MMP-2 Antibody
Description
matrix metallopeptidase 2(MMP2) Homo sapiens This gene is a member of the matrix metalloproteinase (MMP) gene family, that are zinc-dependent enzymes capable of cleaving components of the Extracellular matrix and molecules involved in signal transduction. The protein encoded by this gene is a gelatinase A, type IV collagenase, that contains three fibronectin type II repeats in its catalytic site that allow binding of denatured type IV and V collagen and elastin. Unlike most MMP family members, activation of this protein can occur on the cell membrane. This enzyme can be activated extracellularly by proteases, or, intracellulary by its S-glutathiolation with no requirement for proteolytical removal of the pro-domain. This protein is thought to be involved in multiple pathways including roles in the nervous system, endometrial menstrual breakdown, regulation of vascularization, and metastasis. Mutations in this gene have been associated with Win
Catalog No
C0270
Reactivity
Human, Mouse, Rat, Monkey
Applications
WB, IHC-p, IF/ICC, ELISA
Modification
Unmodified/Total
Source
Polyclonal Rabbit
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
MMP2; CLG4A; 72 kDa type IV collagenase; 72 kDa gelatinase; Gelatinase A; Matrix metalloproteinase-2; MMP-2; TBE-1
Molecular Weight (Da)
73882
Gene Name
MMP2
Protein Name
72 kDa type IV collagenase
Human Gene ID
4313
Human Swiss Prot No.
P08253
Immunogen
The antiserum was produced against synthesized peptide derived from human MMP-2. AA range:611-660
Specificity
MMP-2 Polyclonal Antibody detects endogenous levels of MMP-2 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (15)
Integration of exosomal miR-106a and mesothelial cells facilitates gastric cancer peritoneal dissemination

Author: Meng Zhu, Ning Zhang, Jingwei Ma, Shuixiang He

Date of Publication : 2021-12-25

Emodin suppresses the migration and invasion of melanoma cells

Author: Chi Liu, Liang Chen, Wanchen Wang, Dengke Qin, Chuanlong Jia, Mingjie Yuan, Heng Wang, Yu Guo, Jingjing Zhu, Yiqun Zhou, Haiguang Zhao, Tianyi Liu

Date of Publication : 2021-03-17

Methyl-CpG-binding protein 2 drives the Furin/TGF-β1/Smad axis to promote epithelial–mesenchymal transition in pancreatic cancer cells

Author: Huizhi Wang, Jie Li, Junbo He, Yawen Liu, Wen Feng, Hailang Zhou, Meng Zhou, Hong Wei, Ying Lu, Wanxin Peng, Fengyi Du, Aihua Gong, Min Xu

Date of Publication : 2020-08-26

PHLDA2 regulates EMT and autophagy in colorectal cancer via the PI3K/AKT signaling pathway

Author: Zhan Ma, Shuping Lou, Zheng Jiang

Date of Publication : 2020-05-08

The role of SIRT1 in BMP2-induced chondrogenic differentiation and cartilage maintenance under oxidative stress.

Author: Yang Lu, Li Zhou, Lijun Wang, Shan He, Honglei Ren, Nian Zhou, Zhenming Hu

Date of Publication : 2020-05-01

CBX4 promotes the proliferation and metastasis via regulating BMI‐1 in lung cancer

Author: Changpeng Hu, Qian Zhang, Qin Tang, Huyue Zhou, Wuyi Liu, Jingbin Huang, Yali Liu, Qin Wang, Jing Zhang, Min Zhou, Fangfang Sheng, Wenjing Lai, Jing Tian, Guobing Li, Rong Zhang

Date of Publication : 2019-11-13

Endothelin-1 Activates the Notch Signaling Pathway and Promotes Tumorigenesis in Giant Cell Tumor of the Spine

Author: Yuan Wei, Qian Ming, Li Zhen-Xi, Zhao Cheng-Long, Zhao Jian, Xiao Jian-Ru

Date of Publication : 2019-09-01

Uridine-cytidine kinase 2 promotes metastasis of hepatocellular carcinoma cells via the Stat3 pathway

Author: Qiming Zhou, Hai Jiang, Jianlong Zhang, Wei Yu, Zhenyu Zhou, Pinbo Huang, Jie Wang, Zhiyu Xiao

Date of Publication : 2018-11-26

Phosphoglycerate mutase 1 knockdown inhibits prostate cancer cell growth, migration, and invasion

Author: Yao-An Wen, Bo-Wei Zhou, Dao-Jun Lv, Fang-Peng Shu, Xian-Lu Song, Bin Huang, Chong Wang, Shan-Chao Zhao

Date of Publication : 2017-12-22

YTH domain family 2 orchestrates epithelial-mesenchymal transition/proliferation dichotomy in pancreatic cancer cells

Author: Jixiang Chen, Yaocheng Sun, Xiao Xu, Dawei Wang, Junbo He, Hailang Zhou, Ying Lu, Jian Zeng, Fengyi Du, Aihua Gong, Min Xu

Date of Publication : 2017-11-14

Insulin-like growth factor II mRNA binding protein 3 regulates proliferation, invasion and migration of neuroendocrine cancer cells

Author: Li-Mian Er, Yong Li, Ming-Li Wu, Bin Li, Bi-Bo Tan, Yang Gao, Shi-Jie Wang

Date of Publication : 2017-10-01

Paeonol exerts potential activities to inhibit the growth, migration and invasion of human gastric cancer BGC823 cells via downregulating MMP‑2 and MMP‑9

Author: Zhong‑Kuan Lyu, Chang‑Ling Li, Yan Jin, Yu‑Zhao Liu, Xi Zhang, Fang Zhang, Lu‑Ning Ning, Er‑Shun Liang, Min Ma, Wei Gao, Ming‑Xiang Zhang, De‑Shan Liu

Date of Publication : 2017-09-21

CTGF enhances resistance to 5-FU-mediating cell apoptosis through FAK/MEK/ERK signal pathway in colorectal cancer

Author: Kai Yang, Kai Gao, Gui Hu, Yanguang Wen, Changwei Lin, Xiaorong Li

Date of Publication : 2016-11-30

MeCP2 suppresses LIN28A expression via binding to its methylated-CpG islands in pancreatic cancer cells

Author: Min Xu, Shihui Bian, Jie Li, Junbo He, Hui Chen, Lu Ge, Zhijun Jiao, Youli Zhang, Wanxin Peng, Fengyi Du, Yinyuan Mo, Aihua Gong

Date of Publication : 2016-02-19

GABAergic signaling facilitates breast cancer metastasis by promoting ERK1/2-dependent phosphorylation

Author: Depu Zhang, Xiaowei Li, Ziming Yao, Chuanfei Wei, Nannan Ning, Jingxin Li

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Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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