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FIR Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C10207
Reactivity:Human,Mouse
Applications:WB,IF,ELISA
Modification:Unmodified/Total
Source:Polyclonal,Rabbit,IgG
Storage and Stability:Store at -20°C/1 year

$205
Product Details
Product Name
FIR Antibody
Description
function:Rho-guanine nucleotide exchange factor that activates RAC1. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton.,similarity:Contains 1 DH (DBL-homology) domain.,similarity:Contains 1 FERM domain.,similarity:Contains 2 PH domains.,subunit:Interacts with PLXNA1. Interaction with PLXNA1 or PIP5K1C lowers its guanine nucleotide exchange activity. Dissociates from PLXNA1 when SEMA3A binds to the receptor. Interacts with PIP5K1C via its FERM domain. The interaction with PIP5K1C is enhanced by SEMA3A binding.,
Catalog No
C10207
Reactivity
Human, Mouse
Source
Polyclonal, Rabbit,IgG
Modification
Unmodified/Total
Applications
WB, IF, ELISA
Dilution
WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
FARP2; KIAA0793; PLEKHC3; FERM; RhoGEF and pleckstrin domain-containing protein 2; FERM domain including RhoGEF; FIR; Pleckstrin homology domain-containing family C member 3; PH domain-containing family C member 3
Molecular Weight (Da or kDa)
Gene Name
FARP2
Protein Name
FERM RhoGEF and pleckstrin domain-containing protein 2
Human Gene ID
9855
Human Swiss Prot No.
O94887
Immunogen
The antiserum was produced against synthesized peptide derived from human FIR. AA range:331-380
Specificity
FIR Polyclonal Antibody detects endogenous levels of FIR protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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