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Primary Antibodies
Fra-1 Antibody
Fra-1 Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C10381
Reactivity:Human,Mouse,Rat
Applications:WB,IHC,IF,ELISA
Modification:Unmodified/Total
Source:Polyclonal,Rabbit,IgG
Storage and Stability:Store at -20°C/1 year

$205
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Fra-1 Antibody

Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).

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Product Details
Product Name
Fra-1 Antibody
Description
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014],
Catalog No
C10381
Reactivity
Human, Mouse, Rat
Source
Polyclonal, Rabbit,IgG
Modification
Unmodified/Total
Applications
WB, IHC, IF, ELISA
Dilution
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
FOSL1; FRA1; Fos-related antigen 1; FRA-1
Molecular Weight (Da or kDa)
Gene Name
FOSL1
Protein Name
Fos-related antigen 1
Human Gene ID
8061
Human Swiss Prot No.
P15407
Immunogen
The antiserum was produced against synthesized peptide derived from human Fra-1. AA range:101-150
Specificity
Fra-1 Polyclonal Antibody detects endogenous levels of Fra-1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (5)
Fra‑1 is downregulated in cervical cancer tissues and promotes cervical cancer cell apoptosis by p53 signaling pathway in vitro. INTERNATIONAL JOURNAL OF ONCOLOGY Int J Oncol. 2015 Apr;46(4):1677-1684 WB,IHC Human 1:100/1:300 Cervical cancer tissue

Author: Available in link provided

Date of Publication : Available in link provided

CD24 promotes the proliferation and inhibits the apoptosis of cervical cancer cells in vitro. ONCOLOGY REPORTS Oncol Rep. 2016 Mar;35(3):1593-1601 WB Human 1:300 cervical cancer tissues

Author: Available in link provided

Date of Publication : Available in link provided

Lipopolysaccharide Affects the Proliferation and Glucose Metabolism of Cervical Cancer Cells Through the FRA1/MDM2/p53 Pathway. International Journal of Medical Sciences Int J Med Sci. 2021; 18(4): 1030–1038 WB Human Hela cell, Caski cell

Author: Available in link provided

Date of Publication : Available in link provided

All-trans retinoic acid enhances the effect of Fra-1 to inhibit cell proliferation and metabolism in cervical cancer. BIOTECHNOLOGY LETTERS Biotechnol Lett. 2020 Jun;42(6):1051-1060 WB Human 1:200 Hela cell, Caski cell

Author: Available in link provided

Date of Publication : Available in link provided

YWHAH activates the HMGA1/PI3K/AKT/mTOR signaling pathway by positively regulating Fra-1 to affect the proliferation of gastric cancer cells. Yanhong Zhou WB Human 1:1000 SGC7901 GC cell,AGS GC cell

Author: Available in link provided

Date of Publication : Available in link provided

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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