p70 S6 kinase α Antibody (C10458)

p70 S6 kinase α Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C10458

Reactivity:Human,Mouse,Rat

Applications:WB,IHC-p,IF/ICC,ELISA

Modification:Unmodified/Total

Source:Polyclonal,Rabbit

Storage and Stability:Store at -20°C/1 year

Size:

Price/Quantity $205

Quantity:

Datasheet

SDS

Kinases and Phosphatases

p70 S6 kinase α Antibody

Western blot analysis of lysates from COLO205 and Jurkat cells, using S6K Antibody. The lane on the right is blocked with the synthesized peptide.

Delivery

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

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408-747-0185

Fax

408-747-0145

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Product Details

Product Name

p70 S6 kinase α Antibody

Description

mitogen-activated protein kinase 14(MAPK14) Homo sapiens The protein encoded byThis gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding d

Catalog No

C10458

Reactivity

Human,Mouse,Rat

Source

Polyclonal, Rabbit

Modification

Unmodified/Total

Applications

WB,IHC-p,IF/ICC,ELISA

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

Storage and Stability

Store at -20°C/1 year

Other Name

RPS6KB1; STK14A; Ribosomal protein S6 kinase beta-1; S6K-beta-1; S6K1; 70 kDa ribosomal protein S6 kinase 1; P70S6K1; p70-S6K 1; Ribosomal protein S6 kinase I; Serine/threonine-protein kinase 14A; p70 ribosomal S6 kinase alpha; p70 S6 kinas

Molecular Weight (Da or kDa)

59140

Gene Name

RPS6KB1

Protein Name

Ribosomal protein S6 kinase beta-1

Human Gene ID

Human Swiss Prot No.

P23443

Immunogen

The antiserum was produced against synthesized peptide derived from human S6K. AA range:261-310

Specificity