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Primary Antibodies
Calregulin Antibody
Calregulin Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C10495
Reactivity:Human,Mouse,Rat,Monkey
Applications:WB,FCM,IHC,IF,ELISA
Modification:Unmodified/Total
Source:Polyclonal,Rabbit,IgG
Storage and Stability:Store at -20°C/1 year

$205
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Calregulin Antibody

Immunofluorescence analysis of Hela cell. 1,Calregulin Polyclonal Antibody(green) was diluted at 1:200(4° overnight). 2, Goat Anti Rabbit Alexa Fluor 488 Catalog:SA0665 was diluted at 1:1000(room temperature, 50min). 3 DAPI(blue) 10min.

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Product Details
Product Name
Calregulin Antibody
Description
Calreticulin is a multifunctional protein that acts as a major Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. It is also found in the nucleus, suggesting that it may have a role in transcription regulation. Calreticulin binds to the synthetic peptide KLGFFKR, which is almost identical to an amino acid sequence in the DNA-binding domain of the superfamily of nuclear receptors. Calreticulin binds to antibodies in certain sera of systemic lupus and Sjogren patients which contain anti-Ro/SSA antibodies, it is highly conserved among species, and it is located in the endoplasmic and sarcoplasmic reticulum where it may bind calcium. The amino terminus of calreticulin interacts with the DNA-binding domain of the glucocorticoid receptor and prevents the receptor from binding to its specific glucocorticoid response element. Calreticulin can inhibit the binding of androgen receptor to its
Catalog No
C10495
Reactivity
Human, Mouse, Rat, Monkey
Source
Polyclonal, Rabbit,IgG
Modification
Unmodified/Total
Applications
WB, FCM, IHC, IF, ELISA
Dilution
WB 1:500-2000;Flow Cyt 1:50-200;IHC 1:100-500;IF ICC 1:100-500;ELISA 1:5000-20000
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
CALR; CRTC; Calreticulin; CRP55; Calregulin; Endoplasmic reticulum resident protein 60; ERp60; HACBP; grp60
Molecular Weight (Da or kDa)
Gene Name
CALR
Protein Name
Calreticulin
Human Gene ID
811
Human Swiss Prot No.
P27797
Immunogen
The antiserum was produced against synthesized peptide derived from human CALR. AA range:21-70
Specificity
Calregulin Polyclonal Antibody detects endogenous levels of Calregulin protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (6)
Huaier Induces Immunogenic Cell Death Via CircCLASP1/PKR/eIF2α Signaling Pathway in Triple Negative Breast Cancer WB,FC Human /MDA-MB-231, MDA-MB-468 and 4T1 cells

Author: Available in link provided

Date of Publication : Available in link provided

Tri-component programmable nanoregulator with Three-pronged penetration boosts immunotherapy of Triple-Negative breast cancer Chem Eng J. 2022 Jul;439:135712. IF Mouse

Author: Available in link provided

Date of Publication : Available in link provided

Fe2P nanorods based photothermal therapy combined with immune checkpoint inhibitors for pancreatic cancer. Nanophotonics Nanophotonics-Berlin. 2021 Sep;10(12):3267-3278 FC Mouse Panc02-H7 cell

Author: Available in link provided

Date of Publication : Available in link provided

Identification and Comparison of Differentiation-Related Proteins in Hepatocellular Carcinoma Tissues by Proteomics:. TECHNOLOGY IN CANCER RESEARCH & TREATMENT 2017 Sep 25 WB Human Hepatocellular carcinoma (HCC) tissue

Author: Available in link provided

Date of Publication : Available in link provided

Cu3P/1-MT Nanocomposites Potentiated Photothermal-Immunotherapy. Liewei Wen FC Mouse 4T1 cell

Author: Available in link provided

Date of Publication : Available in link provided

Doxorubicin-Loaded Platelet Decoys for Enhanced Chemoimmunotherapy Against Triple-Negative Breast Cancer in Mice Model. Yunfeng Fu WB,IF,IHC Mouse 4T1 cell-Xenograft 4T1 cell

Author: Available in link provided

Date of Publication : Available in link provided

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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