Description
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. For example, the encoded protein represses the transcription of differentiation-specific genes during keratinocyte proliferation, but this repression is then overcome by differentiation signals. This gene is highly similar to the antennapedia (Antp) gene of Drosophila. [provided by RefSeq, Jul 2008]
Reactivity
Human, Mouse, Rat
Applications
WB, ELISA
Modification
Unmodified/Total
Source
Polyclonal Rabbit
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
HOXA7; HOX1A; Homeobox protein Hox-A7; Homeobox protein Hox 1.1; Homeobox protein Hox-1A
Molecular Weight (Da)
25385
Gene Name
HOXA7
Protein Name
Homeobox protein Hox-A7
Human Gene ID
3204
Human Swiss Prot No.
P31268
Immunogen
The antiserum was produced against synthesized peptide derived from human HOXA7. AA range:91-140
Specificity
Hox-A7 Polyclonal Antibody detects endogenous levels of Hox-A7 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
