PERK Antibody (C11790) | Assay Biotech Inc.

PERK Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C11790

Reactivity:Human,Rat,Mouse

Applications:WB,IHC-p,IF/ICC,ELISA

Modification:Unmodified/Total

Source:Polyclonal,Rabbit

Storage and Stability:Store at -20°C/1 year

Size:

Price/Quantity $205

Quantity:

Datasheet

SDS

Kinases and Phosphatases

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PERK Antibody

Western blot analysis of lysates from HeLa and HepG2 cells, using E2AK3 Antibody. The lane on the right is blocked with the synthesized peptide.

Delivery

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

Telephone

408-747-0185

Fax

408-747-0145

order@assaybiotech.com

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Product Details

Product Name

PERK Antibody

Description

mitogen-activated protein kinase kinase 2(MAP2K2) Homo sapiens The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene. [provided by RefSeq, Jul 2008],

Catalog No

C11790

Reactivity

Human,Rat,Mouse

Source

Polyclonal, Rabbit

Modification

Unmodified/Total

Applications

WB,IHC-p,IF/ICC,ELISA

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

Storage and Stability

Store at -20°C/1 year

Other Name

EIF2AK3; PEK; PERK; Eukaryotic translation initiation factor 2-alpha kinase 3; PRKR-like endoplasmic reticulum kinase; Pancreatic eIF2-alpha kinase; HsPEK

Molecular Weight (Da or kDa)

125147

Gene Name

EIF2AK3

Protein Name

Eukaryotic translation initiation factor 2-alpha kinase 3

Human Gene ID

Human Swiss Prot No.

Q9NZJ5

Immunogen

The antiserum was produced against synthesized peptide derived from human E2AK3. AA range:61-110

Specificity