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GluR-δ2 Antibody
GluR-δ2 Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C12395
Reactivity:Human,Mouse,Rat
Applications:WB,IF,ELISA
Modification:Unmodified/Total
Source:Polyclonal,Rabbit,IgG
Storage and Stability:Store at -20°C/1 year

$205
Product Details
Product Name
GluR-δ2 Antibody
Description
The protein encoded byThis gene is a member of the family of ionotropic glutamate receptors which are the predominant excitatory neurotransmitter receptors in the mammalian brain. The encoded protein is a multi-pass membrane protein that is expressed selectively in cerebellar Purkinje cells. A point mutation in the mouse ortholog, associated with the phenotype named 'lurcher', in the heterozygous state leads to ataxia resulting from selective, cell-autonomous apoptosis of cerebellar Purkinje cells during postnatal development. Mice homozygous for this mutation die shortly after birth from massive loss of mid- and hindbrain neurons during late embryogenesis. This protein also plays a role in synapse organization between parallel fibers and Purkinje cells. Alternate splicing results in multiple transcript variants encoding distinct isoforms. Mutations in this
Catalog No
C12395
Reactivity
Human, Mouse, Rat
Source
Polyclonal, Rabbit,IgG
Modification
Unmodified/Total
Applications
WB, IF, ELISA
Dilution
WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
GRID2; GLURD2; Glutamate receptor delta-2 subunit; GluR delta-2 subunit
Molecular Weight (Da or kDa)
Gene Name
GRID2
Protein Name
Glutamate receptor delta-2 subunit
Human Gene ID
2895
Human Swiss Prot No.
O43424
Immunogen
The antiserum was produced against synthesized peptide derived from human GRID2. AA range:831-880
Specificity
GluR-δ2 Polyclonal Antibody detects endogenous levels of GluR-δ2 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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