Shank 2 Antibody (C18711) | Assay Biotech Inc.

Shank 2 Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C18711

Reactivity:Human,Rat,Mouse

Applications:WB,IHC

Modification:Unmodified/Total

Source:Polyclonal,Rabbit,IgG

Storage and Stability:Store at -20°C/1 year

Size:

Price/Quantity $205

Quantity:

Datasheet

SDS

Neurobiology

Shank 2 Antibody

Immunohistochemical analysis of paraffin-embedded human cervical carcinoma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

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Product Details

Product Name

Shank 2 Antibody

Description

This gene encodes a protein that is a member of the Shank family of synaptic proteins that may function as molecular scaffolds in the postsynaptic density of excitatory synapses. Shank proteins contain multiple domains for protein-protein interaction, including ankyrin repeats, and an SH3 domain. This particular family member contains a PDZ domain, a consensus sequence for cortactin SH3 domain-binding peptides and a sterile alpha motif. The alternative splicing demonstrated in Shank genes has been suggested as a mechanism for regulating the molecular structure of Shank and the spectrum of Shank-interacting proteins in the postsynaptic densities of the adult and developing brain. Alterations in the encoded protein may be associated with susceptibility to autism spectrum disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014],

Catalog No

C18711

Reactivity

Human, Rat, Mouse

Source

Polyclonal, Rabbit,IgG

Modification

Unmodified/Total

Applications

WB, IHC

Dilution

WB 1:500-2000;IHC 1:50-300

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Storage and Stability

Store at -20°C/1 year

Other Name

SHANK2; CORTBP1; KIAA1022; SH3 and multiple ankyrin repeat domains protein 2; Shank2; Cortactin-binding protein 1; CortBP1; Proline-rich synapse-associated protein 1

Molecular Weight (Da or kDa)

Gene Name

SHANK2

Protein Name

SH3 and multiple ankyrin repeat domains protein 2

Human Gene ID

22941

Human Swiss Prot No.

Q9UPX8

Immunogen

The antiserum was produced against synthesized peptide derived from human SHANK2. AA range:331-380

Specificity