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CENP-M Antibody
CENP-M Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C20447
Reactivity:Human,Rat,Mouse
Applications:IHC,IF,WB
Modification:Unmodified/Total
Source:Polyclonal,Rabbit,IgG
Storage and Stability:Store at -20°C/1 year

$205
Product Details
Product Name
CENP-M Antibody
Description
The protein encoded by this gene is an inner protein of the kinetochore, the multi-protein complex that binds spindle microtubules to regulate chromosome segregation during cell division. It belongs to the constitutive centromere-associated network protein group, whose members interact with outer kinetochore proteins and help to maintain centromere identity at each cell division cycle. The protein is structurally related to GTPases but cannot bind guanosine triphosphate. A point mutation that affects interaction with another constitutive centromere-associated network protein, CENP-I, impairs kinetochore assembly and chromosome alignment, suggesting that it is required for kinetochore formation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015],
Catalog No
C20447
Reactivity
Human, Rat, Mouse
Source
Polyclonal, Rabbit,IgG
Modification
Unmodified/Total
Applications
IHC, IF, WB
Dilution
IHC 1:50-200, WB 1:500-2000. IF 1:50-200
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
Centromere protein M (CENP-M; Interphase centromere complex protein 39; Proliferation-associated nuclear element protein 1)
Molecular Weight (Da or kDa)
Gene Name
CENPM C22orf18 ICEN39 PANE1
Protein Name
CENP-M
Human Gene ID
79019
Human Swiss Prot No.
Q9NSP4
Immunogen
Synthesized peptide derived from human CENP-M AA range: 30-110
Specificity
This antibody detects endogenous levels of human CENP-M
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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