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Primary Antibodies
MAD2 Antibody
MAD2 Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C21657
Reactivity:Human,Rat,Mouse
Applications:WB,IP,ELISA
Modification:Unmodified/Total
Source:Polyclonal Rabbit
Storage and Stability:-20°C/1 year

$205
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MAD2 Antibody

Western Blot analysis of A549 cells using MAD2 Polyclonal Antibody diluted at 1:1000

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Product Details
Product Name
MAD2 Antibody
Description
MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. A MAD2 pseudogene has been mapped to chromosome 14. [provided by RefSeq, Jul 2008]
Catalog No
C21657
Reactivity
Human, Rat, Mouse
Applications
WB, IP, ELISA
Modification
Unmodified/Total
Source
Polyclonal Rabbit
Dilution
Western Blot: 1/500 - 1/2000. IP 1:200-500 ELISA: 1/5000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
MAD2L1; MAD2; Mitotic spindle assembly checkpoint protein MAD2A; HsMAD2; Mitotic arrest deficient 2-like protein 1; MAD2-like protein 1
Molecular Weight (Da)
23510
Gene Name
MAD2L1
Protein Name
Mitotic spindle assembly checkpoint protein MAD2A
Human Gene ID
4085
Human Swiss Prot No.
Q13257
Immunogen
The antiserum was produced against synthesized peptide derived from human MAD2L1. AA range:91-140
Specificity
MAD2 Polyclonal Antibody detects endogenous levels of MAD2 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (1)
Phosphorylation of MAD2 at Ser195 Promotes Spindle Checkpoint Defects and Sensitizes Cancer Cells to Radiotherapy in ATM Deficient Cells.

Author: Wang Y, Yu T, Han Y, He Y, Song Y, Guo L, An L, Yang C, Wang F

Date of Publication : 44622

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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