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Primary Antibodies
IL-1β Antibody
IL-1β Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C30147
Reactivity:Human,Mouse,Rat
Applications:WB,IHC-p,IF(paraffin section),ELISA
Modification:Unmodified/Total
Source:Polyclonal Rabbit
Storage and Stability:-20°C/1 year

$205
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IL-1β Antibody

Western Blot analysis of ES-2, U87, PC-3, SHSY5Y, mouse liver cells using IL-1β Polyclonal Antibody. Antibody was diluted at 1:2000. Secondary antibody(catalogNo.:SA0002) was diluted at 1:20000

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Product Details
Product Name
IL-1β Antibody
Description
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]
Catalog No
C30147
Reactivity
Human, Mouse, Rat
Applications
WB, IHC-p, IF(paraffin section), ELISA
Modification
Unmodified/Total
Source
Polyclonal Rabbit
Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
IL1B; IL1F2; Interleukin-1 beta; IL-1 beta; Catabolin
Molecular Weight (Da)
30748
Gene Name
IL1B
Protein Name
Interleukin-1 beta
Human Gene ID
3553
Human Swiss Prot No.
P01584
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human IL1B. AA range:181-230
Specificity
IL-1β Polyclonal Antibody detects endogenous levels of IL-1β protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (16)
Salidroside attenuates high altitude hypobaric hypoxia-induced brain injury in mice via inhibiting NF-κB/NLRP3 pathway

Author: Shengnan Jiang, Fangfang Fan, Lu Yang, Ke Chen, Zhihao Sun, Yi Zhang, Nanjia Cairang, Xiaobo Wang, Xianli Meng

Date of Publication : 2022-05-11

AIP1 suppresses neovascularization by inhibiting the NOX4-induced NLRP3/NLRP6 imbalance in a murine corneal alkali burn model

Author: Li, Qingyu, Hua, Xia, Li, Liangpin, Zhou, Xueyan, Tian, Ye, Deng, Yang, Zhang, Min, Yuan, Xiaoyong, Chi, Wei

Date of Publication : 2022-05-06

Effect of Radix Polygalae extract on the colonic dysfunction in rats induced by chronic restraint stress

Author: Chen-Chen Li, Fan Ye, Chen-Xi Xu, Qi Chang, Xin-Min Liu, Rui-Le Pan

Date of Publication : 2022-05-06

Dietary Fatty Acid Regulation of the NLRP3 Inflammasome via the TLR4/NF-κB Signaling Pathway Affects Chondrocyte Pyroptosis

Author: Jin Xin, Dong Xin, Sun Yingxu, Liu Ziyu, Liu Li, Gu Hailun

Date of Publication : 2022-05-04

Polydatin Improves Sepsis-Associated Encephalopathy by Activating Sirt1 and Reducing p38 Phosphorylation

Author: Lin Huang, Jiawei Chen, Xiaojie Li, Mingxin Huang, Jilou Liu, Na Qin, Zhenhua Zeng, Xingmin Wang, Fen Li, Hong Yang

Date of Publication : 2022-04-18

LncRNA TUG1 Promotes Apoptosis, Invasion, and Angiogenesis of Retinal Endothelial Cells in Retinopathy of Prematurity via MiR-145-5p

Author: Yuexia Wang, Yue Wang, Xue Wang, Yuan Ma, Zhaojin Li, Yu Di, Yuexia Wang, Yue Wang, Xue Wang, Yuan Ma, Zhaojin Li, Yu Di

Date of Publication : 2022-04-04

Maternally expressed gene 3 regulates retinal neovascularization in retinopathy of prematurity

Author: Yu Di, Yue Wang, Yue-Xia Wang, Xue Wang, Yuan Ma, Qing-Zhu Nie

Date of Publication : 2021-11-12

Amelioration of Neuropathic Pain and Attenuation of Neuroinflammation Responses by Tetrahydropalmatine Through the p38MAPK/NF-κB/iNOS Signaling Pathways in Animal and Cellular Models

Author: Hu, Cheng, He, Menglin, Chen, Meijuan, Xu, Qian, Li, Sha, Cui, Yaomei, Qiu, Xizi, Tian, Weiqian

Date of Publication : 2021-11-10

The Regulatory NOD-Like Receptor NLRC5 Promotes Ganglion Cell Death in Ischemic Retinopathy by Inducing Microglial Pyroptosis

Author: Deng Yang, Fu Yunzhao, Sheng Longxiang, Hu Yixin, Su Lishi, Luo Jiawen, Yan Chun, Chi Wei

Date of Publication : 2021-05-20

Oat fiber attenuates circulating oxysterols levels and hepatic inflammation via targeting TLR4 signal pathway in LDL receptor knockout mice

Author: Hui Gao, Chunping Rao, Ruijuan Song, Shufen Han

Date of Publication : 2020-12-16

MCC950 Inhibits NLRP3 Inflammasome and Alleviates Axonal Injures in Early Stages of Diffuse Axonal Injury in Rats

Author: Zhao, Junjie, Guo, Xiaoye, Wang, Bo, Yang, Zhongbo, Huang, Tingqin, Guo, Dan, Zhang, Ming, Song, Jinning

Date of Publication : 2020-05-30

Elevated c-fos expression is correlated with phenotypic switching of human vascular smooth muscle cells derived from lower limb venous varicosities

Author: Zhenyu Guo, Chentao Luo, Ting Zhu, Li Li, Wan Zhang

Date of Publication : 2020-04-28

Small Peptides Compound Isolated from Agkistrodon with Antiarthritic Effect in Collagen-Induced Arthritis Rats

Author: Mei Lijun, Lin Chen, Lei Shanshan, Xu Li, Fan Yong-Sheng

Date of Publication : 2018-04-29

Cereal Fiber Ameliorates High-Fat/Cholesterol-Diet-Induced Atherosclerosis by Modulating the NLRP3 Inflammasome Pathway in ApoE–/– Mice

Author: Ru Zhang, Shufen Han, Zheng Zhang, Weiguo Zhang, Jing Yang, Zhongxiao Wan, Liqiang Qin

Date of Publication : 2018-04-17

Huang-Lian-Jie-Du decoction attenuates cognitive dysfunction of rats with type 2 diabetes by regulating autophagy and NLRP3 inflammasome activation

Author: Ruimin Tian, Xianfeng Liu, Lijia Jing, Lu yang, Na Xie, Ya Hou, Honglin Tao, Yiwen Tao, Jiasi Wu, Xianli Meng

Date of Publication : 44643

Attenuation of Oxidative Stress-Induced Cell Apoptosis and Pyroptosis in RSC96 Cells by Salvianolic Acid B

Author: Wang, Qian-qian, Wang, Meng, Li, Yan, Liu, Yong-hui, Sun, Lian-qing

Date of Publication : 44588

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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