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Primary Antibodies
Keap1 Antibody
Keap1 Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C30246
Reactivity:Human,Mouse,Rat
Applications:WB,IHC-p,IF(paraffin section),ELISA
Modification:Unmodified/Total
Source:Polyclonal Rabbit
Storage and Stability:-20°C/1 year

$205
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Keap1 Antibody

Western Blot analysis of K562 cells using Keap1 Polyclonal Antibody. Antibody was diluted at 1:1000. Secondary antibody(catalogNo.:SA0002) was diluted at 1:20000

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Product Details
Product Name
Keap1 Antibody
Description
This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the Cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq, Jul 2008]
Catalog No
C30246
Reactivity
Human, Mouse, Rat
Applications
WB, IHC-p, IF(paraffin section), ELISA
Modification
Unmodified/Total
Source
Polyclonal Rabbit
Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
KEAP1; INRF2; KIAA0132; KLHL19; Kelch-like ECH-associated protein 1; Cytosolic inhibitor of Nrf2; INrf2; Kelch-like protein 19
Molecular Weight (Da)
68640
Gene Name
KEAP1
Protein Name
Kelch-like ECH-associated protein 1
Human Gene ID
9817
Human Swiss Prot No.
Q14145
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human KEAP1. AA range:411-460
Specificity
Keap1 Polyclonal Antibody detects endogenous levels of Keap1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (4)
The Keap1/Nrf2-ARE signaling pathway is involved in atrazine induced dopaminergic neurons degeneration via microglia activation

Author: Kun Ma, Hao-Yu Wu, Sheng-Yuan Wang, Bai-Xiang Li

Date of Publication : 2021-10-05

Active Peptide KF-8 from Rice Bran Attenuates Oxidative Stress in a Mouse Model of Aging Induced by d-Galactose

Author: Yuqian Wang, Xiaoji Cui, Qinlu Lin, Jie Cai, Liuhuan Tang, Ying Liang

Date of Publication : 2020-09-30

Curcumin protects against methylmercury-induced cytotoxicity in primary rat astrocytes by activating the Nrf2/ARE pathway independently of PKCδ

Author: Bobo Yang, Changsheng Yin, Yun Zhou, Qiang Wang, Yuanyue Jiang, Yu Bai, Hai Qian, Guangwei Xing, Suhua Wang, Fang Li, Yun Feng, Yubin Zhang, Jiyang Cai, Michael Aschner, Rongzhu Lu

Date of Publication : 2019-07-19

Modulations of Keap1-Nrf2 signaling axis by TIIA ameliorated the oxidative stress-induced myocardial apoptosis

Author: Shi-Hai Yan, Ning-Wei Zhao, Zhi-Rong Geng, Jia-Yin Shen, Fu-Ming Liu, Dong Yan, Jie Zhou, Chao Nie, Cheng-Cai Huang, Zhu-Yuan Fang

Date of Publication : 2017-12-06

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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