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Primary Antibodies
SDHB Antibody
SDHB Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C30270
Reactivity:Human,Mouse,Rat,Fish
Applications:WB,IHC,IF,ELISA
Modification:Unmodified/Total
Source:Polyclonal,Rabbit,IgG
Storage and Stability:Store at -20°C/1 year

$205
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SDHB Antibody

Western Blot analysis of HeLa, 293 cells using SDHB Polyclonal Antibody. Secondary antibody(catalog

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Product Details
Product Name
SDHB Antibody
Description
Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. [provided by RefSeq, Jul 2008],
Catalog No
C30270
Reactivity
Human, Mouse, Rat, Fish
Source
Polyclonal, Rabbit,IgG
Modification
Unmodified/Total
Applications
WB, IHC, IF, ELISA
Dilution
WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
SDHB; SDH; SDH1; Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur subunit of complex II; Ip
Molecular Weight (Da or kDa)
Gene Name
SDHB
Protein Name
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit mitochondrial
Human Gene ID
6390
Human Swiss Prot No.
P21912
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human SDHB. AA range:131-180
Specificity
SDHB Polyclonal Antibody detects endogenous levels of SDHB protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (2)
Manganese (Mn)-induced oxidative stress contributes to intestinal lipid deposition via the deacetylation of PPARγ at K339 by SIRT1. DNA AND CELL BIOLOGY. Fish,Human 1:1500 HEK293 cell,IECs

Author: Available in link provided

Date of Publication : Available in link provided

Tenofovir and adefovir down-regulate mitochondrial chaperone TRAP1 and succinate dehydrogenase subunit B to metabolically reprogram glucose metabolism and induce nephrotoxicity. Scientific Reports Sci Rep-Uk. 2017 Apr;7(1):1-15 WB Human HK-2 cell

Author: Available in link provided

Date of Publication : Available in link provided

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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