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MCM6 Antibody

Catalog No : C30289
  • Reactivity
    Human,Mouse,Rat
  • Applications
    WB,ELISA
  • Modification
    Unmodified/Total
  • Source
    Polyclonal Rabbit
  • Storage and Stability
    -20°C/1 year
  • Size
    50 μl
  • Price/Quantity
    $205
  • Quantity
Details
  • Product Name
    MCM6 Antibody
  • Description
    The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric Protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication. Single nucleotide polymorphisms in the intron regions of this gene are associated with differential transcriptional activation of the promoter of the neighboring lactase gene and, thereby, i
  • Catalog No
    C30289
  • Reactivity
    Human, Mouse, Rat
  • Applications
    WB, ELISA
  • Modification
    Unmodified/Total
  • Source
    Polyclonal Rabbit
  • Dilution
    Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
  • Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration
    1 mg/ml
  • Storage and Stability
    -20°C/1 year
  • Other Name
    MCM6; DNA replication licensing factor MCM6; p105MCM
  • Molecular Weight (Da)
    90310
  • Gene Name
    MCM6
  • Protein Name
    DNA replication licensing factor MCM6
  • Human Gene ID
    4175
  • Human Swiss Prot No.
    Q14566
  • Immunogen
    The antiserum was produced against synthesized peptide derived from the Internal region of human MCM6. AA range:331-380
  • Specificity
    MCM6 Polyclonal Antibody detects endogenous levels of MCM6 protein.
  • Formulation
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.