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> Products > Primary Antibodies > CD16 Antibody

CD16 Antibody

Overview Description
Datasheet SDS
   Lymphocyte Signaling   
Catalog No : C30330
  • Reactivity
    Human,Rat,Mouse
  • Applications
    IHC-p,IF(paraffin section),ELISA
  • Modification
    Unmodified/Total
  • Source
    Polyclonal Rabbit
  • Storage and Stability
    -20°C/1 year
  • Size
    50 μl
  • Price/Quantity
    $205
  • Quantity
Add to Cart
Details
  • Product Name
    CD16 Antibody
  • Description
    This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Catalog No
    C30330
  • Reactivity
    Human, Rat, Mouse
  • Applications
    IHC-p, IF(paraffin section), ELISA
  • Modification
    Unmodified/Total
  • Source
    Polyclonal Rabbit
  • Dilution
    IHC-p 1:50-200, ELISA 1:10000-20000
  • Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration
    1 mg/ml
  • Storage and Stability
    -20°C/1 year
  • Other Name
  • Molecular Weight (Da)
  • Gene Name
    FCGR3A CD16A FCG3 FCGR3 IGFR3 FCGR3B CD16B FCG3 FCGR3 IGFR3
  • Protein Name
    Low affinity immunoglobulin gamma Fc region receptor III-A/B (CD16a/b antigen) (Fc-gamma RIII-alpha/beta) (Fc-gamma RIII) (Fc-gamma RIIIa) (FcRIII) (FcRIIIa) (FcR-10) (IgG Fc receptor III-2) (CD antigen CD16a)
  • Human Gene ID
    2214
  • Human Swiss Prot No.
    P08637/O75015
  • Immunogen
    Synthetic peptide from human protein at AA range: 100-150
  • Specificity
    The antibody detects endogenous CD16
  • Formulation
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Application Data
Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:200
Application Data
Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:200
Application Data
Immunohistochemical analysis of paraffin-embedded human-kidney, antibody was diluted at 1:200

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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